trans-4-Hydroxy-L-proline-d4 (Major)

CAS: 2734920-51-3

Ref. TR-H952906

Product Information

• Name: trans-4-Hydroxy-L-proline-d4 (Major)
• Synonyms: trans-4-Hydroxy-L-proline-2,5,5-d4, (-)-4-Hydroxy-2-pyrrolidinecarboxylic Acid-d4, (2S,4R)-(-)-4-Hydroxyproline-d4, (R)-4-Hydroxy-(S)-proline-d4

Description

Applications A labelled trans-4-Hydroxy-L-proline. A natural constituent of animal structural proteins such as collagen and elastin. Several microorganisms producing proline trans-4- and cis-3-hydroxylase were discovered and these enzymes were applied to the industrial production of trans-4- and cis-3-hydroxy-L-proline.
References Langmaier, F. et al.: Int. J. Cosm. Sci., 24, 273 (2002); Lawrence, C., et al.: Biochem. J., 313, 185 (1996); Mori, H., et al.: J. Bacteriol.; 179, 5677 (1997); Clifton, I., et al.: Eur. J. Biochem., 268, 6625 (2001);

• Brand: TRC

Chemical properties

• Molecular weight: 135.15
• Formula: C₅H₅D₄NO₃
• Color/Form: White To Off-White
• InChI: InChI=1S/C5H9NO3/c7-3-1-4(5(8)9)6-2-3/h3-4,6-7H,1-2H2,(H,8,9)/t3-,4+/m1/s1/i2D2,3D,4D
• InChI key: InChIKey=PMMYEEVYMWASQN-AXWUYBSXSA-N
• SMILES: [2H]C1([2H])N[C@]([2H])(C(=O)O)C[C@@]1([2H])O