Hydroxy Urea

CAS: 127-07-1

Ref. TR-H991000

Product Information

• Name: Hydroxy Urea
• Synonyms: N-Hydroxyurea, Biosupressin, Carbamohydroxamic Acid, Carbamoyl Oxime, Cytodrox, Droxia, HU, Hidrix, Hydrea, Hydreia, Hydroxycarbamide, Hydroxycarbamine, N-(Aminocarbonyl)hydroxylamine, Hydroxylurea, Hydura, Hydurea, Litaler, Litalir, N-Carbamoylhydroxylamine, NCI C04831, NSC 32065, Oxyurea, SK 22591, SQ 1089, 1-Hydroxyurea, Amino(Oxido-Λ5-Azanyl)Methanone, Carbamohydroxamic acid, Carbamohydroximic acid, Carbamoyl oxime, Carbamyl hydroxamate, Hidroxicarbamida, Hydrixycarbamide, Hydroxy Urea (D4), Hydroxy urea, Hydroxycarbamid, Hydroxylamine, N-(aminocarbonyl)-, Mylocel, N-(aminocarbonyl)hydroxylamine, N-Hydroxyharnstoff, Nci C04831, Nsc 32065, Onco-carbide, Oxyrea, Siklos, Sk 22591, Sq 1089, Urea, N-hydroxy-, Urea, hydroxy-, Wr 83799, Xromi

Description

Stability Hygroscopic
Applications An anti-neoplastic - inhibits ribonucleoside reductase and DNA replication. A potential therapy for sickle cell anemia which involves the nitrosylation of sickle cell hemoglobin. Horseradish peroxidase catalyzes nitric oxide formation from hydroxyurea in the presence of hydrogen peroxide.
References Ratcliffe, W., et al.: Lancet, 339, 164 (1992), Roodman, G., et al.: Cancer, 80, 1557 (1997), Horwitz, M., et al.: J. Clin. Endocrinol. Metab., 2003, 88, 1603 (2003),

• Brand: TRC

Chemical properties

• Molecular weight: 76.05
• Formula: CH₄N₂O₂
• Color/Form: White Solid
• InChI: InChI=1S/CH4N2O2/c2-1(4)3-5/h5H,(H3,2,3,4)
• InChI key: InChIKey=VSNHCAURESNICA-UHFFFAOYSA-N
• SMILES: NC(=O)NO