Hydroxy Urea-13C,15N2

CAS: 1246814-92-5

Ref. TR-H991002

Product Information

• Name: Hydroxy Urea-13C,15N2
• Synonyms: N-Hydroxyurea-13C,15N2, Biosupressin-13C,15N2, Carbamohydroxamic Acid-13C,15N2, Carbamoyl Oxime-13C,15N2, Cytodrox-13C,15N2, Droxia-13C,15N2, Hydrea-13C,15N2, Hydreia-13C,15N2, Hydroxycarbamide-13C,15N2, Hydroxycarbamine-13C,15N2, N-(Aminocarbonyl)hydroxylamine-13C,15N2, Hydroxylurea-13C,15N2, Hydura-13C,15N2, Litaler-13C,15N2, N-Carbamoylhydroxylamine-13C,15N2, NSC 32065-13C,15N2, Oxyurea-13C,15N2, SK 22591-13C,15N2, SQ 1089-13C,15N2

Description

Applications Labelled Hydroxyurea. An anti-neoplastic - inhibits ribonucleoside reductase and DNA replication. A potential therapy for sickle cell anemia which involves the nitrosylation of sickle cell hemoglobin. Horseradish peroxidase catalyzes nitric oxide formation from hydroxyurea in the presence of hydrogen peroxide.
References Ratcliffe, W., et al.: Lancet, 339, 164 (1992), Roodman, G., et al.: Cancer, 80, 1557 (1997), Horwitz, M., et al.: J. Clin. Endocrinol. Metab., 2003, 88, 1603 (2003),

• Brand: TRC

Chemical properties

• Molecular weight: 79.03
• Formula: CH₄N₂O₂
• Color/Form: Off White Solid
• InChI: InChI=1S/CH4N2O2/c2-1(4)3-5/h5H,(H3,2,3,4)/i1+1,2+1,3+1
• InChI key: InChIKey=VSNHCAURESNICA-VMIGTVKRSA-N
• SMILES: [15NH2][13C](=O)[15NH]O