N-Hydroxy Vortioxetine O-β-D-Glucuronide Sodium Salt

CAS: 1393733-77-1

Ref. TR-H996005

Product Information

• Name: N-Hydroxy Vortioxetine O-β-D-Glucuronide Sodium Salt
• Synonyms: 1-O-[4-[2-[(2,4-Dimethylphenyl)thio]phenyl]-1-piperazinyl]-β-D-glucopyranuronic Acid Sodium Salt
• Brand: TRC
• Description: Applications N-Hydroxy Vortioxetine O-β-D-Glucuronide Sodium Salt, is a metabolite of Vortioxetine (V766000, HBr); a multimodal serotonergic agent which inhibits 5-HT1A, 5-HT1B, 5-HT3A, 5-HT7 receptor and SERT.References Bang-Andersen, B., et al.: J. Med. Chem., 54, 3206 (2011); Mørk, A., et al.: J. Pharmacol. Exp. Ther., 340, 666 (2012); Mørk, A., et al.: Pharmacol. Biochem. Behav. 105C, 41 (2013); Uldam, H.K., et al.: Drug Metab. Dispos., 39, 2264 (2011)

Chemical properties

• Molecular weight: 512.55
• Formula: C₂₄H₂₉N₂NaO₇S
• Color/Form: Neat
• InChI: InChI=1S/C24H30N2O7S.Na/c1-14-7-8-17(15(2)13-14)34-18-6-4-3-5-16(18)25-9-11-26(12-10-25)33-24-21(29)19(27)20(28)22(32-24)23(30)31;/h3-8,13,19-22,24,27-29H,9-12H2,1-2H3,(H,30,31);/q;+1/p-1/t19?,20-,21?,22-,24-;/m0./s1
• InChI key: InChIKey=DIPVCJYEAXXUEF-KPBYOHBFSA-M
• SMILES: Cc1ccc(Sc2ccccc2N2CCN(O[C@@H]3O[C@H](C(=O)O[Na])[C@@H](O)C(O)C3O)CC2)c(C)c1