Hygromycin B

CAS: 31282-04-9

Ref. TR-H997600

Product Information

• Name: Hygromycin B
• Synonyms: D-Streptamine, O-6-amino-6-deoxy-L-glycero-D-galacto-heptopyranosylidene-(1?2-3)-O-ß-D-talopyranosyl-(1?5)-2-deoxy-N3-methyl-, Hygromycin B (7CI), O-6-Amino-6-deoxy-L-glycero-D-galacto-heptopyranosylidene-(1?2-3)-O-ß-D-talopyranosyl-(1?5)-2-deoxy-N3-methyl-D-streptamine, Antihelmycin, Hygromix 2.4, Hygromix-8, Hygrovetin, Hygrovetine, (3'R,3aS,4S,4'R,5'R,6R,6'R,7S,7aS)-4-{[(1R,2S,3R,5S,6R)-3-amino-2,6-dihydroxy-5-(methylamino)cyclohexyl]oxy}-6'-[(1S)-1-amino-2-hydroxyethyl]-6-(hydroxymethyl)octahydro-4H-spiro[1,3-dioxolo[4,5-c]pyran-2,2'-pyran]-3',4',5',7-tetrol (non-preferred name), <span class="text-smallcaps">D</smallcap>-Streptamine, O-6-amino-6-deoxy-<smallcap>L</smallcap>-glycero-<smallcap>D</smallcap>-galacto-heptopyranosylidene-(1→2-3)-O-β-<smallcap>D</span>-talopyranosyl-(1→5)-2-deoxy-N³-methyl-, Hygromycin B - Solution, Hygromycin B Streptomyces hygroscopicus, Hygromycin B solution Streptomyces hygroscopicus, O-6-Amino-6-deoxy-<span class="text-smallcaps">L</smallcap>-glycero-<smallcap>D</smallcap>-galacto-heptopyranosylidene-(1→2-3)-O-β-<smallcap>D</smallcap>-talopyranosyl-(1→5)-2-deoxy-N³-methyl-<smallcap>D</span>-streptamine, hygromycin B aqueous solution, hygromycin B from streptomyces*hygroscopicus, hygromycin B plant cell culture tested
• CAS: 31282-04-9

Description

Applications Hygromycin B is an aminoglycoside and a selective antibiotic agent for the hph gene. Hygromycin B inhibits protein synthesis by interfering with translocation and causing mistranslation at the 70S ribosome
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Cha, T.S., et al.: World. J. Microbiol. Biotechnol., 28, 1771 (2012); Herrero, L., et al.: Biochem., 52, 171 (2013);

• Brand: TRC

Chemical properties

• Molecular weight: 527.52
• Formula: C₂₀H₃₇N₃O₁₃
• Color/Form: Off-White
• InChI: InChI=1S/C20H37N3O13/c1-23-7-2-5(21)9(26)15(10(7)27)33-19-17-16(11(28)8(4-25)32-19)35-20(36-17)18(31)13(30)12(29)14(34-20)6(22)3-24/h5-19,23-31H,2-4,21-22H2,1H3/t5-,6+,7+,8-,9+,10-,11+,12-,13+,14-,15-,16+,17+,18-,19+,20?/m1/s1
• InChI key: InChIKey=GRRNUXAQVGOGFE-BUVMKYKOSA-N
• SMILES: CN[C@H]1C[C@@H](N)[C@H](O)[C@H](OC2O[C@H](CO)[C@@H](O)[C@H]3O[C@]4(O[C@@H](C(N)CO)[C@H](O)[C@@H](O)[C@@H]4O)O[C@@H]23)[C@@H]1O