Product Information
- (3Z)-2,3-Dihydro-3-[[[4-[methyl[2-(4-methyl-1-piperazinyl)acetyl]amino]phenyl]amino]phenylmethylene]-2-oxo-H-Indole-6-carboxylic Acid Methyl Ester-d3
- BIBF 1120-d3
- Ofev-d3
- Vargatef-d3
- Nintedanib-d3
Applications Labelled Intedanib (I666650). It is an indolinone derivative potently blocking VEGF-, PDGF-, and FGF-receptor kinases; an indolinone as triple angiokinase inhibitors. An antitumor agent.
References Sun, L., et al.: J. Med. Chem., 41, 2588 (1998), Xie, H., et al.: J. Med. Chem., 50, 4898 (2007), Hilberg, F., et al.: Cancer Res., 68, 4774 (2008),
Chemical properties
Technical inquiry about: TR-I666652 Intedanib-d3
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