2-Iodobenzotrifluoride

CAS: 444-29-1

Ref. TR-I685630

Product Information

• Name: 2-Iodobenzotrifluoride
• Synonyms: 1-Iodo-2-(trifluoromethyl)benzene, 1-Trifluoromethyl-2-iodobenzene, 2-(Trifluoromethyl)iodobenzene, 2-Iodo-1-trifluoromethylbenzene,2-Iodobenzotrifluoride, 2-Trifluoromethylphenyl IodideNSC 88291, o-(Trifluoromethyl)iodobenzene, alpha,alpha,alpha-Trifluoro-o-iodotoluene, .alpha.,.alpha.,.alpha.-Trifluoro-o-iodo toluene, 1-Iod-2-(trifluormethyl)benzol, 2-Iodo-1-trifluoromethylbenzene, 2-Trifluoromethylphenyl iodide, Benzene, 1-iodo-2- (trifluoromethyl)-, NSC 88291, Toluene, alpha,alpha,alpha-trifluoro-o-iodo-, Toluene, α,α,α-trifluoro-o-iodo-, alpha,alpha,alpha-Trifluoro-2-iodotoluene, o-Iodobenzotrifluoride, o-Trifluoromethyliodobenzene, α,α,α-Trifluoro-o-iodotoluene
• CAS: 444-29-1

Description

Applications 2-Iodobenzotrifluoride acts as a reagent in the preparation, cyclooxygenase-1 inhibitory activity, and docking studies of aminoalkoxyphenylbenzamides. Prepartion and SAR of tricyclic 4,4-dimethyl-3,4-dihydrochromeno[3,4-d]imidazole derivatives as microsomal prostaglandin E2 synthase-1 (mPGES-1) inhibitors.
References Fukai, R., et al.: ChemMedChem, 6, 550 (2011); Muthukaman, N., et al.: Bioorg. Med. Chem. Lett., 27, 2594 (2017)

• Brand: TRC

Chemical properties

• Molecular weight: 272.01
• Formula: C₇H₄F₃I
• Color/Form: Neat
• InChI: InChI=1S/C7H4F3I/c8-7(9,10)5-3-1-2-4-6(5)11/h1-4H
• InChI key: InChIKey=IGZGUYVVBABKOY-UHFFFAOYSA-N
• SMILES: FC(F)(F)c1ccccc1I