Product Information
Name:2-Iodo Adenosine35109-88-7
Controlled Product
Synonyms:
- (2R,3R,4S,5R)-2-(6-amino-2-iodopurin-9-yl)-5-(hydroxymethyl)oxolane-3,4-diol
Brand:TRC
Description:Applications An intermediate in the synthesis of isoguanosine (crotonoside or 2-hydroxyadenosine), a naturally occuring nucleoside analogue of guanosine. Isoguanosine is incorporated into mammalian but not bacterial nucleic acids, stimulates the accumulation of cyclic AMP in the brain, and is an inhibitor of IMP:pyrophosphorylase.References Lowry, B.A., et al.: J. Biol. Chem., 197, 591 (1952), Huang, M., et al.: J. Med. Chem., 15, 462 (1972), Hagen, C., et al.: Biochem. Biophys. Acta, 293, 105 (1973),
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Chemical properties
Molecular weight:393.14
Formula:C10H12IN5O4
Color/Form:Neat
InChI:InChI=1S/C10H12IN5O4/c11-10-14-7(12)4-8(15-10)16(2-13-4)9-6(19)5(18)3(1-17)20-9/h2-3,5-6,9,17-19H,1H2,(H2,12,14,15)/t3-,5-,6-,9-/m1/s1
InChI key:InChIKey=MGEBVSZZNFOIRB-UUOKFMHZSA-N
SMILES:Nc1nc(I)nc2c1ncn2[C@@H]1O[C@H](CO)[C@@H](O)[C@H]1O
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