Product Information
Name:5-Iodotubercidin
Controlled Product
Synonyms:
- (2R,3R,4S,5R)-2-(4-amino-5-iodopyrrolo[2,3-d]pyrimidin-7-yl)-5-(hydroxymethyl)oxolane-3,4-diol
Brand:TRC
Description:Stability Store tightly sealed at 4°C; Light SensitiveApplications 5-Iodotubercidin is an analogue of the antibiotic tubercidin, a pyrrolo[2,3-d]pyrimidine nucleoside antibiotic (1,2,3). A potent inhibitor of adenosine kinase from rat or guinea pig brain. Inhibits uptake of 3H-adenosine into brain slices. 5-Iodotubercidin is a nucleoside transporters inhibitor.References (1) Long, M. and Parker, W. B.: Biochem. Pharmacol., 71, 1671 (2006) (2) Bonilla-Santiago, R., et al.: Mol. Biochem. Parasitol., 162, 149 (2008) (3) Caballero, J., et al.: Bioorg. Med. Chem., 16, 5103 (2008)
Notice:Our products are intended for lab use only. For any other use, please contact us.
Chemical properties
Molecular weight:392.15
Formula:C11H13IN4O4
Color/Form:Neat
InChI:InChI=1S/C11H13IN4O4/c12-4-1-16(10-6(4)9(13)14-3-15-10)11-8(19)7(18)5(2-17)20-11/h1,3,5,7-8,11,17-19H,2H2,(H2,13,14,15)/t5-,7-,8-,11-/m1/s1
InChI key:InChIKey=WHSIXKUPQCKWBY-IOSLPCCCSA-N
SMILES:Nc1ncnc2c1c(I)cn2[C@@H]1O[C@H](CO)[C@@H](O)[C@H]1O
Technical inquiry about: 5-Iodotubercidin
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