Product Information
Name:5-Iodouracil
Controlled Product
Synonyms:
- 5-Iodo-2,4(1H,3H)-pyrimidinedione
- 5-Iodo-2,4-dihydroxypyrimidine
- 5-Iodo-2,4-pyrimidinedione
- 5-Iodopyrimidine-2,4-diol
- NSC 57848
Brand:TRC
Description:Applications 5-Iodouracil is a halogenated pyrimidine that can be used in nucleoprotein photo-crosslinking via RNA substitution. 5-Iodouracil is used in thymidine phosphorylase targeted imaging and therapy. Studies show that DNA N-glycosylase MED1 exhibited higher preference for 5-Iodouracil and halogenated bases over non-halogenated ones.References Meisenheimer, K. et al.: Meth. Enzymol., 318, 88 (2000); Klecker, R.W. Jr. et al.: Cancer Chemother. Pharmacol., 48, 407 (2001); Turner, D.P. et al.: Cancer Res., 66, 7686 (2006);
Notice:Our products are intended for lab use only. For any other use, please contact us.
Chemical properties
Molecular weight:237.98
Formula:C4H3IN2O2
Color/Form:Neat
InChI:InChI=1S/C4H3IN2O2/c5-2-1-6-4(9)7-3(2)8/h1H,(H2,6,7,8,9)
InChI key:InChIKey=KSNXJLQDQOIRIP-UHFFFAOYSA-N
SMILES:Oc1ncc(I)c(O)n1
Technical inquiry about: 5-Iodouracil
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