Irinotecan Lactone Impurity
CAS: 143490-53-3
Ref. TR-I767520
| 25mg | 2,457.00 € | ||
| 50mg | 4,302.00 € | ||
| 2500µg | 368.00 € |
Estimated delivery in United States, on Thursday 19 Dec 2024
Product Information
Name:
Irinotecan Lactone Impurity
Controlled Product
Synonyms:
- [1,4'-Bipiperidine]-1'-carboxylic acid
- 3,10-diethyl-11,13-dihydro-1,13-dioxo-1H,3H-furo[3',4':6,7]indolizino[1,2-b]quinolin-8-yl ester
- [1,4'-Bipiperidine]-1'-carboxylic Acid 3,10-Diethyl-11,13-dihydro-1,13-dioxo-1H,3H- furo[3',4':6,7]indolizino[1,2-b]quinolin-8-yl Ester
Description:
Applications A lactone impurity of Irinotecan (I767500), a DNA topoisomerase inhibitor. A photodegradation product of a camptothecin derivative used as an anticancer drug.
References Akimoto, K. et al.: J. Chrom. 734, 401 (1996); Kunimoto, T., et al.: Cancer Res., 47, 5944 (1987); Shimada, Y., et al.: J. Clin. Oncol., 11, 909 (1993); Chen, A., et al.: Annu. Rev. Pharmacol. Toxicol., 34, 191 (1994);
Notice:
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Brand:
TRC
Long term storage:
Notes:
Chemical properties
Molecular weight:
556.65
Formula:
C32H36N4O5
Color/Form:
Neat
InChI:
InChI=1S/C32H36N4O5/c1-3-21-22-16-20(40-32(39)35-14-10-19(11-15-35)34-12-6-5-7-13-34)8-9-25(22)33-29-24(21)18-36-26(29)17-23-27(4-2)41-31(38)28(23)30(36)37/h8-9,16-17,19,27H,3-7,10-15,18H2,1-2H3
InChI key:
InChIKey=MPKLBQKGQFVIOG-UHFFFAOYSA-N
SMILES:
CCc1c2c(nc3ccc(OC(=O)N4CCC(N5CCCCC5)CC4)cc13)-c1cc3c(c(=O)n1C2)C(=O)OC3CC
MDL:
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Technical inquiry about: TR-I767520 Irinotecan Lactone Impurity
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