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(R)-Irofulven
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(R)-Irofulven

CAS: 158440-71-2

Ref. TR-I769500

25mg
14,918.00 €
Estimated delivery in United States, on Tuesday 17 Dec 2024

Product Information

Name:
(R)-Irofulven
Controlled Product
Synonyms:
  • (6'R)-6'-Hydroxy-3'-(hydroxymethyl)-2',4',6'-trimethylspiro[cyclopropane-1,5'-[5H]inden]-7'(6'H)-one
  • (-)-(Hydroxymethyl)acylfulvene
  • (-)-Irofulven
  • HMAF
  • MGI 114
  • NSC 683863
  • (6'R)-6'-hydroxy-3'-(hydroxymethyl)-2',4',6'-trimethylspiro[cyclopropane-1,5'-inden]-7'(6'H)-one
  • (6′R)-6′-Hydroxy-3′-(hydroxymethyl)-2′,4′,6′-trimethylspiro[cyclopropane-1,5′-[5H]inden]-7′(6′H)-one
  • 6-Hmaf
  • Hmaf
  • See more synonyms
  • Hydroxymethylacylfulvene
  • Irofulven
  • Mgi-114
  • Nsc-683863
  • Spiro[cyclopropane-1,5′-[5H]inden]-7′(6′H)-one, 6′-hydroxy-3′-(hydroxymethyl)-2′,4′,6′-trimethyl-, (6′R)-
  • Spiro[cyclopropane-1,5′-[5H]inden]-7′(6′H)-one, 6′-hydroxy-3′-(hydroxymethyl)-2′,4′,6′-trimethyl-, (R)-
Description:

Applications Semi-synrhetic antitumor agent derived from Illudin S. Inhibits DNA synthesis and induces apoptosis in tumor cells. Antineoplastic.
References Woynarowski, J.M., et al.: Biochem. Pharmacol., 54, 1181 (1997), Alexandre, J., et al.: Clin. Cancer Res., 10, 3377 (2004), Senzer, N., et al.: Am. J. Clin. Oncol., 28, 36 (2005),

Notice:
Our products are intended for lab use only. For any other use, please contact us.
Brand:
TRC
Long term storage:
Notes:

Chemical properties

Molecular weight:
246.31
Formula:
C15H18O3
Color/Form:
Neat
InChI:
InChI=1S/C15H18O3/c1-8-6-10-12(11(8)7-16)9(2)15(4-5-15)14(3,18)13(10)17/h6,16,18H,4-5,7H2,1-3H3/t14-/m0/s1
InChI key:
InChIKey=NICJCIQSJJKZAH-AWEZNQCLSA-N
SMILES:
CC1=C(CO)C2=C(C)C3(CC3)[C@@](C)(O)C(=O)C2=C1
MDL:
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EINECS:
Merck:
HS code:

Hazard Info

UN Number:
EQ:
Class:
H Statements:
P Statements:
Forbidden to fly:
Hazard Info:
Packing Group:
LQ:

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