Isometronidazole

CAS: 705-19-1

Ref. TR-I821340

Product Information

• Name: Isometronidazole
• Synonyms: 2-(2-Methyl-4-nitro-1H-imidazol-1-yl)ethanol, Metronidazole Imp. E (EP), 2-Methyl-4-nitro-1H-imidazole-1-ethanol, 2-Methyl-4-nitroimidazole-1-ethanol, 1-(2-Hydroxyethyl)-2-methyl-4-nitroimidazole, Izoklion, Mizonidazole, RP 8979, SC-16427, Metronidazole Impurity E, 1-(2-Hydroxyethyl)-2-methyl-4-nitro-1H-imidazole, 2-(2-Methyl-4-nitro-imidazol-1-yl)-ethanol, 2-(2-Methyl-4-nitroimidazol-1-yl)ethanol, Imidazole-1-ethanol, 2-methyl-4-nitro-, Imidazole-1-ethanol,2-methyl-4-nitro- (7CI,8CI), Rp 8979, Sc-16427

Description

Impurity Metronidazole EP Impurity E
Applications Isometronidazole (Metronidazole EP Impurity E) is an impurity of Metronidazole (M338880), a chemotherapeutic agent that is used as a first line defense against Clostridium difficile (C.diff). Isometronidazole is also a hypoxic cell sensitizer in humans and mice.
References Hentschel, M. & Schmidt, W.: Die Pharm., 47, 221 (1992); Musher, D., et al.: Clin. Inf. Dis., 40, 1586 (2005); Rosenkranz, H. & Speck, W.: Biochem. Biophys. Res. Comm., 66, 520 (1975)

• Brand: TRC

Chemical properties

• Molecular weight: 171.15
• Formula: C₆H₉N₃O₃
• Color/Form: Neat
• InChI: InChI=1S/C6H9N3O3/c1-5-7-6(9(11)12)4-8(5)2-3-10/h4,10H,2-3H2,1H3
• SMILES: Cc1nc([N+](=O)[O-])cn1CCO