Isometronidazole-D4

CAS: 2469037-64-5

Ref. TR-I821342

Product Information

• Name: Isometronidazole-D4
• Synonyms: 2-(2-Methyl-4-nitro-1H-imidazol-1-yl)ethanol-1,1,2,2-D4, Isometronidazole-d4 (hydroxyethyl-d4), 2-Methyl-4-nitroimidazole-1-ethanol-1,1,2,2-d4, 1-(2-Hydroxyethyl-d4)-2-methyl-4-nitroimidazole

Description

Applications Isometronidazole-D4 is a labelled analogue of Isometronidazole (I821342). Isometronidazole is an impurity of Metronidazole (M338880), a chemotherapeutic agent that is used as a first line defense against Clostridium difficile (C.diff). Isometronidazole is also a hypoxic cell sensitizer in humans and mice.
References Hentschel, M. & Schmidt, W.: Die Pharm., 47, 221 (1992); Musher, D., et al.: Clin. Inf. Dis., 40, 1586 (2005); Rosenkranz, H. & Speck, W.: Biochem. Biophys. Res. Comm., 66, 520 (1975)

• Brand: TRC

Chemical properties

• Molecular weight: 175.18
• Formula: C₆D₄H₅N₃O₃
• Color/Form: Neat
• InChI: InChI=1S/C6H9N3O3/c1-5-7-6(9(11)12)4-8(5)2-3-10/h4,10H,2-3H2,1H3/i2D2,3D2
• SMILES: [2H]C([2H])(O)C([2H])([2H])n1cc([N+](=O)[O-])nc1C