Product Information
Name:Isoniazid-d4
Controlled Product
Synonyms:
- 4-Pyridine-2,3,5,6-d4-carboxylic acid
- hydrazide (9CI)
- 4-Pyridine-2,3,5,6-d4-carboxylic acid hydrazide
- Isonicotinoyl-d4-hydrazide
Brand:TRC
Description:Applications Labelled Isoniazid. Antibiotic for treatment of Mycobacterium tuberculosis, inhibits mycolic acid biosynthesis. Metabolized by hepatic N-acetyltransferase (NAT) and cytochrome P450 2E1 (CYP2E1) to form hepatotoxins. Selectively induces expression of CYP2E1. Reversibly inhibits CYP2C19 and CYP3A4 activities, and mechanistically inactivates CYP1A2, CYP2A6, CYP2C19 and CYP3A4 at clinically relevant concentrations. Antibacterial (tuberculostatic).References Brewer, G.A., et al.: Anal. Profiles Drug Subs., 6, 183 (1977), Weber, W.W., et al.: Clin. Pharmacokinet., 4, 401 (1979)
Notice:Our products are intended for lab use only. For any other use, please contact us.
Chemical properties
Molecular weight:141.16
Formula:C62H4H3N3O
Color/Form:White To Light Beige
InChI:InChI=1S/C6H7N3O/c7-9-6(10)5-1-3-8-4-2-5/h1-4H,7H2,(H,9,10)/i1D,2D,3D,4D
InChI key:InChIKey=QRXWMOHMRWLFEY-RHQRLBAQSA-N
SMILES:[2H]c1nc([2H])c([2H])c(C(=O)NN)c1[2H]
Technical inquiry about: Isoniazid-d4
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