TR-I872253 - n-isopropyl-n-methylamine-hydrochloride | 54565-61-6

<p>Applications N-Isopropyl-N-methylamine-d7 Hydrochloride is an intermediate in the synthesis of Saflufenacil-d7 (S081802). Saflufenacil-d7 is the labeled version of Saflufenacil (S081800), which is a herbicide of the pyrimidinedione chemical class used for the preplant burndown and selective preemergence dicot weed control in different field crops. It was found to inhibit protoporphyrinogen IX oxidase (PPO) enzyme.<br>References Knezevic, S., et al.: Crop Prot., 29, 148 (2010); Grossmann, K., et al.: Weed Sci., 58, 1 (2010)<br></p>

The experimental kinetic study of the adsorption process of methylene (CH2) on C-(4-isopropyl-[1,2,3]thiadiazol-5-yl)-methylamine hydrochloride (MTDZH) was carried out at various temperatures. The adsorption process is an equilibrium process, and the data were fitted to the Langmuir model with parameters K and q. The Langmuir adsorption isotherm equation is given by: q = K(C/Cmax)^n where q is the amount of MTDZH adsorbed at equilibrium (mg/g), C/Cmax is the concentration ratio of MTDZH in solution to that in solid phase, K is the equilibrium constant for MTDZH (Lmol/(mol*g)), and n is the power law exponent. The values of n obtained from regression analysis are 1.87 ± 0.