N-Isopropylnortropine Methobromide (Impurity)

CAS: 58005-18-8

Ref. TR-I872685

Product Information

• Name: N-Isopropylnortropine Methobromide (Impurity)
• Synonyms: 8-Azoniabicyclo[3.2.1]octane, 3-hydroxy-8-methyl-8-(1-methylethyl)-, bromide (1:1), (3-endo,8-syn)-, 8-Azoniabicyclo[3.2.1]octane, 3-hydroxy-8-methyl-8-(1-methylethyl)-, bromide, (endo,syn)- (9CI), (8R)-3a-Hydroxy-8-isopropyl-1aH,5aH-tropanium bromide, N-Isopropylnortropine methobromide, (1R,3r,5S,8r)-3-Hydroxy-8-methyl-8-(1-methylethyl)-8-azoniabicyclo[3.2.1]octane Bromide

Description

Impurity Ipratropium EP Impurity A
Applications N-Isopropylnortropine Methobromide (Ipratropium EP Impurity A) is an impurity of Ipratropium (Bromide Monohydrate: I740500), an Atropine (A794625)-like bronchodilator that acts via an anticholinergic pathway, and is used to treat patients with chronic bronchitis, cardiac obstructive pulmonary disease (COPD) and asthma.
References Baigelman, W. & Chodosh, S.: CHEST J., 71, 324 (1977); Groggins, R., et al.: Arch. Dis. Child., 56, 342 (1981); Sichletidis, L., et al.: Int. J. Clin. Prac., 53, 185 (1998)

• Brand: TRC

Chemical properties

• Molecular weight: 264.20
• Formula: C₁₁H₂₂NO·Br
• Color/Form: White To Off-White
• InChI: /h8-11,13H,4-7H2,1-3H3, InChI=1S/C11H22NO.BrH/c1-8(2)12(3)9-4-5-10(12)7-11(13)6-9, /p-1/t9-,10+,11+,12+, 1H/q+1