8-Isoprostaglandin E1

CAS: 21003-46-3

Ref. TR-I918350

Product Information

• Name: 8-Isoprostaglandin E1
• Synonyms: Prost-13-en-1-oic acid, 11,15-dihydroxy-9-oxo-, (8ß,11a,13E,15S)-, Cyclopentaneheptanoic acid, 3-hydroxy-2-(3-hydroxy-1-octenyl)-5-oxo-, stereoisomer (8CI), (8ß,11a,13E,15S)-11,15-Dihydroxy-9-oxoprost-13-en-1-oic acid, 11a,15-(S)-Dihydroxy-9-oxo-13-trans-, (8β,11α,13E,15S)-11,15-Dihydroxy-9-oxoprost-13-en-1-oic acid, 11α,15-(S)-Dihydroxy-9-oxo-13-trans-8-isoprostenoic acid, 21003-46-3, 8-Iso-PGE₁, 8-Isoprostaglandin E₁, Cyclopentaneheptanoic acid, 3-hydroxy-2-(3-hydroxy-1-octenyl)-5-oxo-, stereoisomer, Isoprostaglandin E₁, Ovinonic acid, Prost-13-en-1-oic acid, 11,15-dihydroxy-9-oxo-, (8β,11α,13E,15S)-

Description

Applications 8-Isoprostaglandin E1 has vasodilatory and electrophysiological actions porcine coronary artery. It also inhibits acetylcholine release from parasympathetic nerves innervating guinea-pig trachea mediation by prostanoid EP3 receptors.
References Zhang Y., et al., J. Pharmacol. Exp. Ther.: 305, 1054-1060 (2003); Clarke D. L., et al., Br. J. Pharmacol.: 141, 600-609 (2004)

• Brand: TRC

Chemical properties

• Molecular weight: 354.481
• Formula: C₂₀H₃₄O₅
• Color/Form: Neat
• InChI: InChI=1S/C20H34O5/c1-2-3-6-9-15(21)12-13-17-16(18(22)14-19(17)23)10-7-4-5-8-11-20(24)25/h12-13,15-17,19,21,23H,2-11,14H2,1H3,(H,24,25)/b13-12+/t15-,16-,17+,19+/m0/s1
• InChI key: InChIKey=GMVPRGQOIOIIMI-JCPCGATGSA-N
• SMILES: CCCCC[C@H](O)/C=C/[C@@H]1[C@H](CCCCCCC(=O)O)C(=O)C[C@H]1O