Isradipine

CAS: 75695-93-1

Ref. TR-I925000

Product Information

• Name: Isradipine
• Synonyms: Methyl 1-methylethyl (4RS)-4-(2,1,3-benzoxadiazol-4-yl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate, 2,1,3-Benzoxadiazole, 3,5-pyridinedicarboxylic acid deriv., 3,5-Pyridinedicarboxylic acid, 4-(2,1,3-benzoxadiazol-4-yl)-1,4-dihydro-2,6-dimethyl-, 3-methyl 5-(1-methylethyl) ester, 3,5-Pyridinedicarboxylic acid, 4-(2,1,3-benzoxadiazol-4-yl)-1,4-dihydro-2,6-dimethyl-, methyl 1-methylethyl ester, 3,5-Pyridinedicarboxylic acid, 4-(4-benzofurazanyl)-1,4-dihydro-2,6-dimethyl-, methyl 1-methylethyl ester, 3-O-Methyl 5-O-propan-2-yl 4-(2,1,3-benzoxadiazol-4-yl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate, Clivoten, DynaCirc, DynaCirc CR, DynaCire, DynaCire CR, Dynacrine, Esradin, Isopropyl methyl (+-)-4-(4-benzofurazanyl)-1,4-dihydro-2,6-dimethyl-3,5-pyridinedicarboxylate, Isradipin, Isradipine [USAN:INN:BAN], Isradipino, Isradipino [Spanish], Isradipinum, Isradipinum [Latin], Isrodipine, Lomir, Pn 200, Pn 200-110, Prescal, Rebriden, Unii-Yo1Uk1S598

Description

Applications Isradipine is a dihydropyridine calcium channel blocker. Antihypertensive and antianginal.
References Nelson, E.B., et al.: Clin. Pharmacol. Ther., 40, 694 (1986); Hof, R.P., et al.: J. Cardiovasc. Pharmacol., 8, 221 (1986);

• Brand: TRC

Chemical properties

• Molecular weight: 371.39
• Formula: C₁₉H₂₁N₃O₅
• Color/Form: Neat
• InChI: InChI=1S/C19H21N3O5/c1-9(2)26-19(24)15-11(4)20-10(3)14(18(23)25-5)16(15)12-7-6-8-13-17(12)22-27-21-13/h6-9,16,20H,1-5H3
• InChI key: InChIKey=HMJIYCCIJYRONP-UHFFFAOYSA-N
• SMILES: COC(=O)C1=C(C)NC(C)=C(C(=O)OC(C)C)C1c1cccc2nonc12