Product Information
- 1H-Benzotriazol-1-yl(2,4-dichlorophenyl)-methanone
- ITSA-1
- Methanone, 1H-1,2,3-benzotriazol-1-yl(2,4-dichlorophenyl)-
- 1H-Benzotriazol-1-yl(2,4-dichlorophenyl)methanone
Applications Histone deacetylase (HDAC) inhibitors are able to interrupt cell cycle progression in transformed cell lines and may be explored as new clinical agents in cancer therapy. 1-(2,4-Dichlorobenzoyl)-1H-benzotriazole has been shown to suppress the biological effects induced by the HDAC inhibitor, Trichostatin A (T774710).
References Koeller, K. M., et al.: Chem. Biol. 10, 397 (2003); Vigushin, D., et al.: Clin. Cancer Res. 7, 971 (2001)
Chemical properties
Technical inquiry about: TR-I937560 1-(2,4-Dichlorobenzoyl)-1H-benzotriazole
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