Product Information
Name:(-)-α-Kainic Acid Lithium Salt
Controlled Product
Synonyms:
- Lithium 2-((2S,3S,4S)-2-carboxy-4-(prop-1-en-2-yl)pyrrolidin-3-yl)acetate
Brand:TRC
Description:Applications (-)-α-Kainic Acid Lithium Salt is a naturally occurring neuroexcitatory chemical that is an selective agonist for a subtype of ionotropic glutamate receptor. Administration of (-)-α-Kainic Acid has been shown to increase production of reactive oxygen species, mitochondrial dysfunction, and apoptosis in neurons in many regions of the brain, particularly in the hippocampal subregions and in the hilus of dentate gyrus.References Wacker, D.A., et al.: Synlett, 503 (1997), Dunleavy, M., et al.: J. Molec. Neurosci., 49, 202 (2013); Zhang, J., et al.: Neuron., 76, 1133 (2012); Yamada, J., et al.: Neurosci., 226, 119 (2012); Wang,Q., et al.: Mol. Neurobiol., 31, 3 (2005)’
Notice:Our products are intended for lab use only. For any other use, please contact us.
Chemical properties
Molecular weight:219.163
Formula:C10H14LiNO4
Color/Form:Neat
InChI:InChI=1S/C10H15NO4.Li/c1-5(2)7-4-11-9(10(14)15)6(7)3-8(12)13;/h6-7,9,11H,1,3-4H2,2H3,(H,12,13)(H,14,15);/q;+1/p-1/t6-,7+,9-;/m0./s1
InChI key:InChIKey=NOUMCWSOFPNXAY-SLGZUKMRSA-M
SMILES:[Li]OC(=O)C[C@H]1[C@@H](C(=C)C)CN[C@@H]1C(=O)O
Technical inquiry about: (-)-α-Kainic Acid Lithium Salt
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