rac-Kavain-d3

CAS: 3155-48-4

Ref. TR-K145492

Product Information

• Name: rac-Kavain-d3
• Synonyms: 5,6-Dihydro-4-methoxy-6-[(1E)-2-phenylethenyl]-2H-pyran-2-one-d3, DL-Kawain-d3, dl-Kavain-d3, (+)-Kavain, (±)-Kawain, 2H-Pyran-2-one, 5,6-dihydro-4-methoxy-6-(2-phenylethenyl)-, (E)-, 2H-Pyran-2-one, 5,6-dihydro-4-methoxy-6-[(1E)-2-phenylethenyl]-, 2H-Pyran-2-one, 5,6-dihydro-4-methoxy-6-styryl-, (±)-, 4-methoxy-6-[(E)-2-phenylethenyl]-5,6-dihydro-2H-pyran-2-one, 5,6-Dihydro-4-methoxy-6-[(1E)-2-phenylethenyl]-2H-pyran-2-one, <span class="text-smallcaps">DL</span>-Kawain, dl-Kavain, DL-Kawain

Description

Stability Light and Moisture Sensitive
Applications Isotope Labelled analogue of rac-Kavain (K145490), the main kavalactone found in the roots of the kava plant. Kavain is known to exhibit anticonvulsive properties by attenuating vascular smooth muscle contraction through interactions with voltage-dependent sodium and calcium channels. rac-Kavain was shown in recent research to exhibit protective properties on anaerobic glycolysis, ATP content and intracellular calcium and sodium of anoxic brain vesicles.
References Gleitz, J., et al: Neuropharmacol., 35, 1743 (1997); Hashimoto, T., et al.: Phytomedicine, 10, 309 (2003); Mulholland, P.J., et al.: Brain. Res., 945, 106 (2002);

• Brand: TRC

Chemical properties

• Molecular weight: 233.28
• Formula: C₁₄D₃H₁₁O₃
• Color/Form: Neat
• InChI: InChI=1S/C14H14O3/c1-16-13-9-12(17-14(15)10-13)8-7-11-5-3-2-4-6-11/h2-8,10,12H,9H2,1H3/b8-7+/i1D3
• InChI key: InChIKey=XEAQIWGXBXCYFX-MXMZWNBPSA-N
• SMILES: [2H]C([2H])([2H])OC1=CC(=O)OC(/C=C/c2ccccc2)C1