Estimated delivery in United States, on Tuesday 2 Jul 2024
Product Information
Name:
Kenpaullone
Synonyms:
- 9-Bromo-7,12-dihydroindolo[3,2-d][1]benzazepin-6(5H)-one
- 9-Bromopaullone
- NSC 664704
- 8-Bromo-7,12-Dihydro-Indolo[3,2-D][1]-Benzazepin-6(5H)-One
- 9-Bromo-7,12-Dihydro-Indolo[3,2-D][1]Benzazepin-6(5H)-One
- 9-Bromo-7,12-dihydro-indolo[3,2-d][1]benzazepin-6(5H)-one, NSC 664704
- Indolo[3,2-d][1]benzazepin-6(5H)-one, 9-bromo-7,12-dihydro-
- Nsc-664704
CAS:
Description:
Applications The paullones are a novel class of kinase inhibitors, initially identified as CDK inhibitors. Kenpaullone has been found to be a useful GSK-3ß inhibitor (IC50=23nM).
References Zaharevitz, D.W., et al.: Cancer Res., 59, 2566 (1999), Leclerc, S., et al.: J. Biol. Chem., 276, 251 (2001), Bain, J., et al.: Biochem. J., in press.
Brand:
TRC
Long term storage:
Notes:
Chemical properties
Molecular weight:
327.18
Formula:
C16H11BrN2O
Color/Form:
Dark Yellow to Very Dark Yellow Solid
InChI:
InChI=1S/C16H11BrN2O/c17-9-5-6-14-11(7-9)12-8-15(20)18-13-4-2-1-3-10(13)16(12)19-14/h1-7,19H,8H2,(H,18,20)
InChI key:
InChIKey=QQUXFYAWXPMDOE-UHFFFAOYSA-N
SMILES:
O=C1Cc2c([nH]c3ccc(Br)cc23)-c2ccccc2N1
MDL:
Melting point:
Boiling point:
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Density:
Concentration:
EINECS:
Merck:
HS code:
Technical inquiry about: TR-K162500 Kenpaullone
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