Product Information
- 2-[[(4R)-4-[(3R,5S,8R,9S,10S,13R,14S,17R)-3-hydroxy-10,13-dimethyl-7-oxo-1,2,3,4,5,6,8,9,11,12,14,15,16,17-tetradecahydrocyclopenta[a]phenanthren-17-yl]pentanoyl]amino]ethanesulfonic acid
- 7-Oxolithocholic acid-taurine conjugate
- 7-Ketolithocholic acid-taurine conjugate
- Ethanesulfonic acid, 2-[[(3α,5β)-3-hydroxy-7,24-dioxocholan-24-yl]amino]-
- 2-[[(3α,5β)-3-Hydroxy-7,24-dioxocholan-24-yl]amino]ethanesulfonic acid
Applications 7-Ketolithocholic Acid-taurine Conjugate is a bile acid conjugate and metabolite of Taurolithocholic Acid (T009100) with antiinflammatory activity. Taurochenodeoxycholic Acid has been shown to inhibit hepatocyte apoptosis through suppression of Bid translocation to mitochondria.
References Emerman, S. et al.: J. Biol. Chem., 242, 661 (1967); Takikawa, Y. et al.: Falk Symp., 120, 249 (2001); Li, P. et al.: Zhong. Shour. Xue., 28, 1317 (2008);
Chemical properties
Technical inquiry about: TR-K175030 3α-Hydroxy-7-oxocholanoyltaurine
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