Labetalol Hydrochloride

CAS: 32780-64-6

Ref. TR-L096495

Product Information

• Name: Labetalol Hydrochloride
• Synonyms: Benzamide, 2-hydroxy-5-[1-hydroxy-2-[(1-methyl-3-phenylpropyl)amino]ethyl]-, hydrochloride (1:1), Benzamide, 2-hydroxy-5-[1-hydroxy-2-[(1-methyl-3-phenylpropyl)amino]ethyl]-, monohydrochloride (9CI), Salicylamide, 5-[1-hydroxy-2-[(1-methyl-3-phenylpropyl)amino]ethyl]-, monohydrochloride (8CI), AH 5158 hydrochloride, AH 5158A, Amipress, Ipolab, Labelol, Labracol, NSC 290312, Normodyne, Presdate, Pressalolo, Sch 15719W, Trandate, Vescal, 2-Hydroxy-5-{1-Hydroxy-2-[(4-Phenylbutan-2-Yl)Amino]Ethyl}Benzamide, 2-Hydroxy-5-{1-Hydroxy-2-[(4-Phenylbutan-2-Yl)Amino]Ethyl}Benzamide Hydrochloride (1:1), Ah 5158A, Benzamide, 2-hydroxy-5-[1-hydroxy-2-[(1-methyl-3-phenylpropyl)amino]ethyl]-, hydrochloride (1:1), Benzamide, 2-hydroxy-5-[1-hydroxy-2-[(1-methyl-3-phenylpropyl)amino]ethyl]-, monohydrochloride, Labetalol HCl, Labetalol Hydrochoride, Salicylamide, 5-[1-hydroxy-2-[(1-methyl-3-phenylpropyl)amino]ethyl]-, monohydrochloride

Description

Applications Labetalol is a specific competitive antagonist at both α-and β-adrenergic receptor sites. Labetalol is used as an antihypertensive.
References Sybertz, E.J. et al.: J. Pharmacol. Exp. Ther., 218, 435 (1981); Clifton, J.E. et al.: J. Med. Chem., 25, 670 (1982); Goa, K.L. et al.: Drugs, 37, 583 (1989);

• Brand: TRC

Chemical properties

• Molecular weight: 364.87
• Formula: C₁₉H₂₄N₂O₃·ClH
• Color/Form: White
• InChI: InChI=1S/C19H24N2O3.ClH/c1-13(7-8-14-5-3-2-4-6-14)21-12-18(23)15-9-10-17(22)16(11-15)19(20)24;/h2-6,9-11,13,18,21-23H,7-8,12H2,1H3,(H2,20,24);1H
• InChI key: InChIKey=WQVZLXWQESQGIF-UHFFFAOYSA-N
• SMILES: CC(CCc1ccccc1)NCC(O)c1ccc(O)c(C(N)=O)c1.Cl