(R,R)-Labetalol Hydrochloride

CAS: 75659-08-4

Ref. TR-L096500

Product Information

• Name: (R,R)-Labetalol Hydrochloride
• Synonyms: Benzamide, 2-hydroxy-5-[(1R)-1-hydroxy-2-[[(1R)-1-methyl-3-phenylpropyl]amino]ethyl]-, hydrochloride (1:1), Benzamide, 2-hydroxy-5-[(1R)-1-hydroxy-2-[[(1R)-1-methyl-3-phenylpropyl]amino]ethyl]-, monohydrochloride (9CI), Benzamide, 2-hydroxy-5-[1-hydroxy-2-[(1-methyl-3-phenylpropyl)amino]ethyl]-, monohydrochloride, [R-(R*,R*)]-, Dilevalol hydrochloride, Sch 19927 HCl, (-)-5-((1R)-1-Hydroxy-2-(((1R)-1-methyl-3-phenylpropyl)amino)ethyl)salicylamide monohydrochloride, (R,R)-5-(1-Hydroxy-2-((1-methyl-3-phenylpropyl)amino)ethyl)salicylamide hydrochloride, (R,R)-Dilevalol hydrochloride, (R,R)-Labetalol hydrochloride, 2-hydroxy-5-[(1R)-1-hydroxy-2-{[(2R)-4-phenylbutan-2-yl]amino}ethyl]benzamide hydrochloride (1:1), Benzamide, 2-hydroxy-5-(1-hydroxy-2-((1-methyl-3-phenylpropyl)amino)ethyl)-, monohydrochloride, (R-(R*,R*))-, Benzamide, 2-hydroxy-5-[(1R)-1-hydroxy-2-[[(1R)-1-methyl-3-phenylpropyl]amino]ethyl]-, hydrochloride (1:1), Benzamide, 2-hydroxy-5-[(1R)-1-hydroxy-2-[[(1R)-1-methyl-3-phenylpropyl]amino]ethyl]-, monohydrochloride, Dilevalol HCl, Dilevalol hydrochloride [USAN:JAN], Sch 19927, Unii-O5Obt75D2C

Description

Stability Hygroscopic
Applications (R,R)-Labetalol Hydrochloride is a specific competitive antagonist at both α-and β-adrenergic receptor sites. (R,R)-Labetalol Hydrochloride is also used as an antihypertensive.
References Sybertz, E.J., et al.: J. Pharmacol. Exp. Ther., 218, 435 (1981), Clifton, J.E., et al.: J. Med. Chem., 25, 670 (1982), Goa, K.L., et al.: Drugs, 37, 583 (1989),

• Brand: TRC

Chemical properties

• Molecular weight: 364.87
• Formula: C₁₉H₂₄N₂O₃·ClH
• Color/Form: Neat
• InChI: InChI=1S/C19H24N2O3.ClH/c1-13(7-8-14-5-3-2-4-6-14)21-12-18(23)15-9-10-17(22)16(11-15)19(20)24;/h2-6,9-11,13,18,21-23H,7-8,12H2,1H3,(H2,20,24);1H/t13-,18+;/m1./s1
• InChI key: InChIKey=WQVZLXWQESQGIF-UHFFFAOYSA-N
• SMILES: CC(CCc1ccccc1)NCC(O)c1ccc(O)c(C(N)=O)c1.Cl