Product Information
Name:(+)-Lactacystin Allyl Ester
Controlled Product
Synonyms:
- Lactacystin Allyl Ester
Brand:TRC
Description:
Applications The precursor to Lactacystin, a selective and potent inhibitor of proteasome-mediated degradation of ubiquitin-tagged proteins. A Streptomyces metabolite that acts as a highly specific inhibitor of the 20S proteasome (MCP: multicatalytic proteinase complex).
References Fenteany, G., et al.: Science, 268, 726 (1995), Fenteany, G., et al.: Proc. Natl. Acad. Sci. USA, 91, 3358 (1994),
Notice:Our products are intended for lab use only. For any other use, please contact us.
Chemical properties
Molecular weight:416.489
Formula:C18H28N2O7S
Color/Form:Neat
InChI:InChI=1S/C18H28N2O7S/c1-6-7-27-16(25)12(19-11(5)21)8-28-17(26)18(13(22)9(2)3)14(23)10(4)15(24)20-18/h6,9-10,12-14,22-23H,1,7-8H2,2-5H3,(H,19,21)(H,20,24)/t10-,12+,13-,14+,18?/m1/s1
InChI key:InChIKey=RYUOBJYLYRDIEH-QEISHDMDSA-N
SMILES:C=CCOC(=O)[C@H](CSC(=O)C1([C@H](O)C(C)C)NC(=O)[C@H](C)[C@@H]1O)NC(C)=O
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