Lamivudine Dimer

CAS: 134678-17-4

Ref. TR-L172480

Product Information

• Name: Lamivudine Dimer
• Synonyms: 1-[(2R,5S)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl]-4-[[[1-[(2R,5S)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl]-2-oxopyrimidin-4-yl]amino]methylamino]pyrimidin-2-one, (-) 2'-Deoxy-3'-thiacytidine, (-)-1-[(2R,5S)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl]cystosine, (-)-2¢ -Deoxy-3¢ -Thiacytidine, (-)-Bch-189, (-)Ngpb-21, (2R-cis)-4-Amino-1-[2-(hydroxymethyl)-1,3-oxathiolan-5-yl]-2(1H)-pyrimidinone, (2R-cis)-4-amino-1-, 1,3-Oxathiolane, 2(1H)-pyrimidinone deriv., 2(1H)-Pyrimidinone, 4-amino-1-[(2R,5S)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl]-, 2(1H)-Pyrimidinone,4-amino-1-[2-(hydroxymethyl)-1,3-oxathiolan-5-yl]-,(2R-cis)-, 2-Hydroxymethyl-5-(cytosin-1-yl)-1,3-oxathiolane, 3'-Thia-2',3'-Dideoxcytidine, 3TC, 3¢ -Thia-2¢ ,3¢ -Dideoxycytidine, 4-Amino-1-[(2R,5S)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl]-2(1H)-pyrimidinone, 4-amino-1-[(2R,5S)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl]pyrimidin-2(1H)-one, 4-amino-1-[(2S,5R)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl]pyrimidin-2(1H)-one, <span class="text-smallcaps">L</span>-SddC, Epivir, Epivir HBV, Gr 109714X, Gr109714X, Hepitec, Heptodin, Heptovir, Hiviral, Lamidine, Lamivir, Virolam, Zeffix, Zefix, cis(-)-2-Hydroxymethyl-5-(cytosin-1-yl)-1,3-oxathiolane, β-<span class="text-smallcaps">L</span>-2′,3′-Dideoxy-3′-thiacytidine, β-<span class="text-smallcaps">L</span>-3′-Thia-2′,3′-dideoxycytidine, 3￠-thia-2￠,3￠-dideoxycytidine, (-)-2￠-deoxy-3￠-thiacytidine

Description

Applications Lamivudine Dimer is an impurity of Lamivudine (L172500); a potent nucleoside reverse transcriptase inhibitor and antiviral agent. Lamivudine has also been used for treatment of chronic hepatitis B.
References Morris, D.M., J. Pharm. Biomed. Anal., 12, 255 (1944); Nevens, B.F., et al.: Gastroenterology, 113, 1258 (1997); Perry, C.M., et al.: Drugs, 53, 657 (1977)

• Brand: TRC

Chemical properties

• Molecular weight: 470.523
• Formula: C₁₇H₂₂N₆O₆S₂
• Color/Form: Neat
• InChI: InChI=1S/C17H22N6O6S2/c24-5-14-28-12(7-30-14)22-3-1-10(20-16(22)26)18-9-19-11-2-4-23(17(27)21-11)13-8-31-15(6-25)29-13/h1-4,12-15,24-25H,5-9H2,(H,18,20,26)(H,19,21,27)/t12-,13-,14+,15+/m0/s1
• InChI key: InChIKey=FFUUGVLVHXYVFJ-BYNSBNAKSA-N
• SMILES: O=c1nc(NCNc2ccn([C@@H]3CS[C@H](CO)O3)c(=O)n2)ccn1[C@@H]1CS[C@H](CO)O1