Lamivudine

CAS: 134678-17-4

Ref. TR-L172500

Product Information

• Name: Lamivudine
• Synonyms: 2(1H)-Pyrimidinone, 4-amino-1-[(2R,5S)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl]-, 2(1H)-Pyrimidinone, 4-amino-1-[2-(hydroxymethyl)-1,3-oxathiolan-5-yl]-, (2R-cis)-, 1,3-Oxathiolane, 2(1H)-pyrimidinone deriv., (-)-2'-Deoxy-3'-thiacytidine, (-)-BCH 189, 2-Hydroxymethyl-5-(cytosin-1-yl)-1,3-oxathiolane, 3TC, BCH 189, (-)-, Epivir, Epivir HBV, GR 109714X, Hepitec, Heptodin, Heptovir, L-SddC, Lamivir, Virolam, Zeffix, Zefix, cis(-)-2-Hydroxymethyl-5-(cytosin-1-yl)-1,3-oxathiolane, beta-L-2',3'-Dideoxy-3'-thiacytidine, beta-L-3'-Thia-2',3'-dideoxycytidine, GR 109714X, 3TC, GR 111720X, GR 135522X, Lamivudine GR109714X, BP Zidovudine and Lamivudine Impurity Standard, Ph Eur Lamivudine for system suitability 1, BP Lamivudine Impurity Standard, Ph Eur Lamivudine for system suitability 2, (-) 2'-Deoxy-3'-thiacytidine, (-)-1-[(2R,5S)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl]cystosine, (-)-2¢ -Deoxy-3¢ -Thiacytidine, (-)-Bch-189, (-)Ngpb-21, (2R-cis)-4-Amino-1-[2-(hydroxymethyl)-1,3-oxathiolan-5-yl]-2(1H)-pyrimidinone, (2R-cis)-4-amino-1-, 1,3-Oxathiolane, 2(1H)-pyrimidinone deriv., 2(1H)-Pyrimidinone, 4-amino-1-[(2R,5S)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl]-, 2(1H)-Pyrimidinone,4-amino-1-[2-(hydroxymethyl)-1,3-oxathiolan-5-yl]-,(2R-cis)-, 3'-Thia-2',3'-Dideoxcytidine, 3¢ -Thia-2¢ ,3¢ -Dideoxycytidine, 4-Amino-1-[(2R,5S)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl]-2(1H)-pyrimidinone, 4-amino-1-[(2R,5S)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl]pyrimidin-2(1H)-one, 4-amino-1-[(2S,5R)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl]pyrimidin-2(1H)-one, <span class="text-smallcaps">L</span>-SddC, Gr 109714X, Gr109714X, Hiviral, Lamidine, β-<span class="text-smallcaps">L</span>-2′,3′-Dideoxy-3′-thiacytidine, β-<span class="text-smallcaps">L</span>-3′-Thia-2′,3′-dideoxycytidine, 3￠-thia-2￠,3￠-dideoxycytidine, (-)-2￠-deoxy-3￠-thiacytidine

Description

Applications Lamivudine is a potent nucleoside reverse transcriptase inhibitor. Antiviral. Lamivudine has been used for treatment of chronic hepatitis B.
References Morris, D.M., J. Pharm. Biomed. Anal., 12, 255 (1944), Nevens, B.F., et al.: Gastroenterology, 113, 1258 (1997), Perry, C.M., et al.: Drugs, 53, 657 (1977),

• Brand: TRC

Chemical properties

• Molecular weight: 229.26
• Formula: C₈H₁₁N₃O₃S
• Color/Form: White
• InChI: InChI=1S/C8H11N3O3S/c9-5-1-2-11(8(13)10-5)6-4-15-7(3-12)14-6/h1-2,6-7,12H,3-4H2,(H2,9,10,13)/t6-,7+/m0/s1
• InChI key: InChIKey=JTEGQNOMFQHVDC-NKWVEPMBSA-N
• SMILES: Nc1ccn([C@@H]2CS[C@H](CO)O2)c(=O)n1