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Leflunomide-d4
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Leflunomide-d4

CAS: 1189987-23-2

Ref. TR-L322752

1mg
244.00 €
10mg
1,585.00 €
Estimated delivery in United States, on Wednesday 15 Jan 2025

Product Information

Name:
Leflunomide-d4
Controlled Product
Synonyms:
  • 5-Methyl-N-[2,3,5,6-tetradeuterio-4-(trifluoromethyl)phenyl]-1,2-oxazole-4-carboxamide
  • 5-Methyl-N-[4-(trifluoromethyl)phenyl-2,3,5,6-d4]-4-isoxazolecarboxamide
  • Leflunomide-D4 (phenyl-D4)
Description:

Applications An immunosuppressive. Inhibits T and B cell proliferation. Activity is attributed mainly to its metabolite, a malononitrile derivative, which is beleived to inhibit dihydroorotate dehydrogenase as well as several protein tyrosine kinases.This compound is suitable for dihydroorotate dehydrogenase (DHODH) related research.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Vrenken, T., et al.: J. Hepatol., 49, 799 (2008), Mazzucco, G., et al.: Clin. Nephrol., 70, 163 (2008), Davies, M., et al.: J. Med. Chem., 52, 2683 (2009),

Notice:
Our products are intended for lab use only. For any other use, please contact us.
Brand:
TRC
Long term storage:
Notes:

Chemical properties

Molecular weight:
274.23
Formula:
C12H5D4F3N2O2
Color/Form:
Neat
InChI:
InChI=1S/C12H9F3N2O2/c1-7-10(6-16-19-7)11(18)17-9-4-2-8(3-5-9)12(13,14)15/h2-6H,1H3,(H,17,18)/i2D,3D,4D,5D
InChI key:
InChIKey=VHOGYURTWQBHIL-QFFDRWTDSA-N
SMILES:
[2H]c1c([2H])c(C(F)(F)F)c([2H])c([2H])c1NC(=O)c1cnoc1C
MDL:
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EINECS:
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HS code:

Hazard Info

UN Number:
EQ:
Class:
H Statements:
P Statements:
Forbidden to fly:
Hazard Info:
Packing Group:
LQ:

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