Levosimendan Cyanoacetamide Hydrazone Impurity

CAS: 274263-65-9

Ref. TR-L378015

Product Information

• Name: Levosimendan Cyanoacetamide Hydrazone Impurity
• Synonyms: 2-Cyano-2-[[4-[(4R)-1,4,5,6-tetrahydro-4-methyl-6-oxo-3-pyridazinyl]phenyl]hydrazono]-acetamide, 2-Cyano-2-[2-[4-[(4R)-1,4,5,6-tetrahydro-4-methyl-6-oxo-3-pyridazinyl]phenyl]hydrazinylidene]-acetamide
• Brand: TRC
• Description: Applications Levosimendan Cyanoacetamide Hydrazone Impurity is an impurity of Levosimendan (L378000) which is a bioactive enantiomer of racemate, Simendan. It is a positive inotropic agent with vasodilating activity and also cardiotonic.References Sandell, E.-P., et al.: J. Cardiovasc. Pharmacol., 26, S57 (1995); Pagel, P.S., et al.: Cardiovasc. Drug Rev., 14, 286 (1996)

Chemical properties

• Molecular weight: 298.3
• Formula: C₁₄H₁₄N₆O₂
• Color/Form: Off-White To Dark Orange
• InChI: InChI=1S/C14H14N6O2/c1-8-6-12(21)19-20-13(8)9-2-4-10(5-3-9)17-18-11(7-15)14(16)22/h2-5,8,17H,6H2,1H3,(H2,16,22)(H,19,21)/b18-11+/t8-/m1/s1
• SMILES: C[C@@H]1CC(=O)NN=C1c1ccc(N/N=C(\C#N)C(N)=O)cc1