Licofelone

CAS: 156897-06-2

Ref. TR-L397730

Product Information

• Name: Licofelone
• Synonyms: 1H-Pyrrolizine-5-acetic acid, 6-(4-chlorophenyl)-2,3-dihydro-2,2-dimethyl-7-phenyl-, ML 3000, [2,2-Dimethyl-6-(4-chlorophenyl)-7-phenyl-2,3-dihydro-1H-pyrrolizin-5-yl]acetic acid, 1H-Pyrrolizine-5-acetic acid, 6-(4-chlorophenyl)-2,3-dihydro-2,2-dimethyl-7-phenyl-, 2-[2-(4-Chlorophenyl)-6,6-Dimethyl-1-Phenyl-5,7-Dihydropyrrolizin-3-Yl]Acetic Acid, 2-[6-(4-Chlorophenyl)-2,2-dimethyl-7-phenyl-2,3-dihydro-1H-pyrrolizin-5-yl]acetic acid, 6-(4-Chlorophenyl)-2,3-dihydro-2,2-dimethyl-7-phenyl- 1H-pyrrolizine-5-acetic Acid, Licofelone, ML-3000, Ml 3000, [6-(4-chlorophenyl)-2,2-dimethyl-7-phenyl-2,3-dihydro-1H-pyrrolizin-5-yl]acetic acid
• CAS: 156897-06-2

Description

Applications Dual inhibitor of cyclooxygenase and 5-lipoxygenase. Anti-inflammatory.
References Laufer, S.A., et al.: J. Med. Chem., 37, 1894 (1994), Tries, S., et al.: Inflamm. Res., 51, 135 (2002), Moreau, M., et al.: J. Vet. Pharmacol. Ther., 28, 81 (2005),

• Brand: TRC

Chemical properties

• Molecular weight: 379.88
• Formula: C₂₃H₂₂ClNO₂
• Color/Form: Off-White to Light Yellow Solid
• InChI: InChI=1S/C23H22ClNO2/c1-23(2)13-19-22(15-6-4-3-5-7-15)21(16-8-10-17(24)11-9-16)18(12-20(26)27)25(19)14-23/h3-11H,12-14H2,1-2H3,(H,26,27)
• InChI key: InChIKey=UAWXGRJVZSAUSZ-UHFFFAOYSA-N
• SMILES: CC1(C)Cc2c(-c3ccccc3)c(-c3ccc(Cl)cc3)c(CC(=O)O)n2C1