Lincomycin-D3

CAS: 154-21-2

Ref. TR-L466202

Product Information

• Name: Lincomycin-D3
• Synonyms: (2S-trans)-Methyl 6,8-Dideoxy-6-[[(1-methyl-d3-4-propyl-2-pyrrolidinyl)carbonyl]amino]-1-thio-D-erythro-a-D-galacto-octopyranoside, Lincocin-d3, Lincogap-d3, NSC 70731-d3, U 10149a-d3, <span class="text-smallcaps">D</smallcap>-erythro-<smallcap>D</smallcap>-galacto-Octopyranoside, methyl 6,8-dideoxy-6-(1-methyl-4-propyl-<smallcap>L</span>-2-pyrrolidinecarboxamido)-1-thio-, trans-α-, <span class="text-smallcaps">D</smallcap>-erythro-α-<smallcap>D</span>-galacto-Octopyranoside, methyl 6,8-dideoxy-6-[[(1-methyl-4-propyl-2-pyrrolidinyl)carbonyl]amino]-1-thio-, (2S-trans)-, <span class="text-smallcaps">D</smallcap>-erythro-α-<smallcap>D</span>-galacto-Octopyranoside, methyl 6,8-dideoxy-6-[[[(2S,4R)-1-methyl-4-propyl-2-pyrrolidinyl]carbonyl]amino]-1-thio-, Cillimycin, D-erythro-D-galacto-Octopyranoside, methyl 6,8-dideoxy-6-(1-methyl-4-propyl-L-2-pyrrolidinecarboxamido)-1-thio-, trans-α-, D-erythro-α-D-galacto-Octopyranoside, methyl 6,8-dideoxy-6-[[(1-methyl-4-propyl-2-pyrrolidinyl)carbonyl]amino]-1-thio-, (2S-trans)-, D-erythro-α-D-galacto-Octopyranoside, methyl 6,8-dideoxy-6-[[[(2S,4R)-1-methyl-4-propyl-2-pyrrolidinyl]carbonyl]amin o]-1-thio-, Jiemycin, Lincolcina, Lincolnensin, Lincomicina, Lincomix, Lincomycin, Lincomycin A, Lincomycine, Medoglycine, Methyl 6,8-dideoxy-6-[[[(2S,4R)-1-methyl-4-propyl-2-pyrrolidinyl]carbonyl]amino]-1-thio-<span class="text-smallcaps">D</smallcap>-erythro-α-<smallcap>D</span>-galacto-octopyranoside, Nsc 70731, U 10,149A, U 10149
• CAS: 154-21-2

Description

Stability Hygroscopic
Applications Labelled Lincomycin. An antibiotic produced by Streptomyces lincolnensis. Lincomycin is a lincosamide antibiotic that forms cross-links within the peptidyl transferase loop region of the 23S rRNA. Inhibits bacterial protein synthesis. Antibacterial.
References Mason, D. J., et al.: Antimicrob. Agents Chemother., 555 (1962), Gray, et al.: Toxicol. Appl. Pharmacol., 6, 476 (1964), Muti, H. Y., et al.: Anal. Profiles Drug Subs. Excip., 23, 269 (1994)

• Brand: TRC

Chemical properties

• Molecular weight: 409.56
• Formula: C₁₈H₃₁D₃N₂O₆S
• Color/Form: White To Yellow
• InChI: InChI=1S/C18H34N2O6S/c1-5-6-10-7-11(20(3)8-10)17(25)19-12(9(2)21)16-14(23)13(22)15(24)18(26-16)27-4/h9-16,18,21-24H,5-8H2,1-4H3,(H,19,25)/t9-,10+,11-,12+,13-,14+,15+,16+,18+/m0/s1/i3D3
• InChI key: InChIKey=OJMMVQQUTAEWLP-FNAQOLEFSA-N
• SMILES: [2H]C([2H])([2H])N1C[C@H](CCC)CC1C(=O)N[C@H]([C@@H](C)O)[C@H]1O[C@H](SC)C(O)C(O)[C@H]1O