Lithocholylglycine

CAS: 474-74-8

Ref. TR-L469200

Product Information

• Name: Lithocholylglycine
• Synonyms: 2-[[(4R)-4-[(3R,5R,8R,9S,10S,13R,14S,17R)-3-hydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]pentanoyl]amino]acetic acid, 3α-Hydroxy-5β-cholanic acid glycine ester, 3α-Hydroxy-5β-cholanoylglycine, 3α-Hydroxy-N-(carboxymethyl)-5β-cholan-24-amide, 5β-Cholan-24-amide, N-(carboxymethyl)-3α-hydroxy-, 79252-50-9, Cholane, glycine deriv., Glycine, N-(3α-hydroxy-5β-cholan-24-oyl)-, Glycine, N-[(3α,5β)-3-hydroxy-24-oxocholan-24-yl]-, Glycolithocholic acid, Lithocholic acid glycine conjugate, N-(3α-Hydroxy-5β-cholanoyl)glycine, N-[(3α,5β)-3-Hydroxy-24-oxocholan-24-yl]glycine

Description

Applications A metabolite in human hepatic bile. A lithocholic acid analog that inhibit sialyltransferase.
References Ishikawa, H., et al.: J. Lipid. Res., 40, 1920 (1999), Gustafsson, U., et al.: Eur. J. Clin. Invest., 30, 1099 (2000), Gowda, G., et al.: Lipids, 41, 591 (2006), Lindon, J., et al.: Pharm. Res., 23, 1075 (2006),

• Brand: TRC

Chemical properties

• Molecular weight: 433.62
• Formula: C₂₆H₄₃NO₄
• Color/Form: Off-White
• InChI: InChI=1S/C26H43NO4/c1-16(4-9-23(29)27-15-24(30)31)20-7-8-21-19-6-5-17-14-18(28)10-12-25(17,2)22(19)11-13-26(20,21)3/h16-22,28H,4-15H2,1-3H3,(H,27,29)(H,30,31)/t16-,17-,18-,19+,20-,21+,22+,25+,26-/m1/s1
• InChI key: InChIKey=XBSQTYHEGZTYJE-OETIFKLTSA-N
• SMILES: C[C@H](CCC(=O)NCC(=O)O)[C@H]1CC[C@H]2[C@@H]3CC[C@@H]4C[C@H](O)CC[C@]4(C)[C@H]3CC[C@@]21C