Lofexidine Hydrochloride

CAS: 21498-08-8

Ref. TR-L469390

Product Information

• Name: Lofexidine Hydrochloride
• Synonyms: 1H-Imidazole, 2-[1-(2,6-dichlorophenoxy)ethyl]-4,5-dihydro-, hydrochloride (1:1), 1H-Imidazole, 2-[1-(2,6-dichlorophenoxy)ethyl]-4,5-dihydro-, monohydrochloride (9CI), 2-Imidazoline, 2-[1-(2,6-dichlorophenoxy)ethyl]-, monohydrochloride (8CI), Baq 168, Britlofex, Lofetensin, Loxacor, MDL 14042, (±)-2-(1-(2,6-Dichlorophenoxy)ethyl)-2-imidazoline Hydrochloride, 1H-Imidazole, 2-[1-(2,6-dichlorophenoxy)ethyl]-4,5-dihydro-, monohydrochloride, 1H-imidazole, 2-[1-(2,6-dichlorophenoxy)ethyl]-4,5-dihydro-, hydrochloride (1:1), 2-(1-(2,6-Dichlorophenoxy)ethyl)-4,5-dihydro-1H-imidazole Monohydrochloride, 2-(1-(2,6-Dichlorophenoxy)ethyl)-4,5-dihydro-1H-imidazole hydrochloride, 2-Imidazoline, 2-[1-(2,6-dichlorophenoxy)ethyl]-, monohydrochloride, 2-[1-(2,6-Dichlorophenoxy)ethyl]-4,5-dihydro-1H-imidazole hydrochloride (1:1), Mdl 14042, Rmi 14042A, Lofexidine hydrochloride

Description

Applications α2-Adrenoceptor agonist related structurally to Clonidine. Used in treatment of opioid withdrawal symptoms; antihypertensive.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Velly, J., et al.: J. Pharmacol., 8, 351 (1977), Jarrot, B., et al.: Biochem. Pharmacol., 28, 141 (1979), Birch, P., at al.: Brit. J. Pharmacol., 68, 107 (1980),

• Brand: TRC

Chemical properties

• Molecular weight: 295.59
• Formula: C₁₁H₁₂Cl₂N₂O·ClH
• Color/Form: Neat
• InChI: InChI=1S/C11H12Cl2N2O.ClH/c1-7(11-14-5-6-15-11)16-10-8(12)3-2-4-9(10)13, 1H, /h2-4,7H,5-6H2,1H3,(H,14,15)
• InChI key: InChIKey=DWWHMKBNNNZGHF-UHFFFAOYSA-N
• SMILES: CC(Oc1c(Cl)cccc1Cl)C1=NCCN1.Cl