Product Information
Name:Lometrexol Hydrate
Controlled Product
Synonyms:
- N-[4-[2-[(6R)-2-Amino-3,4,5,6,7,8-hexahydro-4-oxopyrido[2,3-d]pyrimidin-6-yl]ethyl]benzoyl]-L-glutamic Acid Hydrate
- LY 264618 Hydrate
Brand:TRC
Description:Applications It is an antifolate which inhibits glycinamide ribonucleotide formyltransferase (GARFT), an enzyme essential for de novo purine synthesis. Lometrexol has activity against tumors which are refractory to other drugs, notably Methotrexate. Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the packageReferences Gibbs, D., et al.: Cancer Res., 65, 11721 (2005), Gangjee, A., et al.: J. Med. Chem., 48, 5329 (2005), Hilgenbrink, A., et al.: J. Pharm. Sci., 94, 2135 (2005),
Notice:Our products are intended for lab use only. For any other use, please contact us.
Chemical properties
Molecular weight:443.45 + x(18.02)
Formula:C21H25N5O6·xH2O
Color/Form:Neat
Technical inquiry about: Lometrexol Hydrate
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