Lovastatin

CAS: 75330-75-5

Ref. TR-L472225

Product Information

• Name: Lovastatin
• Synonyms: Simvastatin Imp. E (EP), (+)-Mevinolin, Altocor, Altoprev, Antibiotic MB 530B, L 154803, Lestric, Lostatin, Lovacard, Lovalip, Lovastatin lactone, Lovex, MK 803, MSD 803, Mevacor, Mevinacor, Mevinolin, Mevlor, Monacolin K, Monacolin K lactone, NSC 633781, Sivlor, Butanoic acid, 2-methyl-, 1,2,3,7,8,8a-hexahydro-3,7-dimethyl-8-[2-(tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl)ethyl]-1-naphthalenyl ester, [1S-[1α(R*),3α,7β,8β(2S*,4S*),8aβ]]-
• Brand: TRC
• Description: Impurity Simvastatin EP Impurity EApplications Lovastatin (Simvastatin EP Impurity E) is an antihypercholesterolemic agent. A fungal metabolite, which is a potent inhibitor of HMG-CoA reductase.References Bilheimer, D.W., et al.: Proc. Nat. Acad. Sci. USA, 80, 4124 (1983),

Chemical properties

• Molecular weight: 404.54
• Formula: C₂₄H₃₆O₅
• Color/Form: White To Light Yellow
• InChI: InChI=1S/C24H36O5/c1-5-15(3)24(27)29-21-11-14(2)10-17-7-6-16(4)20(23(17)21)9-8-19-12-18(25)13-22(26)28-19/h6-7,10,14-16,18-21,23,25H,5,8-9,11-13H2,1-4H3/t14-,15-,16-,18+,19+,20-,21-,23-/m0/s1
• InChI key: InChIKey=PCZOHLXUXFIOCF-BXMDZJJMSA-N
• SMILES: CC[C@H](C)C(=O)O[C@H]1C[C@@H](C)C=C2C=C[C@H](C)[C@H](CC[C@@H]3C[C@@H](O)CC(=O)O3)[C@H]21