Loxapine N-Oxide

CAS: 25967-34-4

Ref. TR-L472755

Product Information

• Name: Loxapine N-Oxide
• Synonyms: Dibenz[b,f][1,4]oxazepine, 2-chloro-11-(4-methyl-4-oxido-1-piperazinyl)-, Dibenz[b,f][1,4]oxazepine, 2-chloro-11-(4-methyl-1-piperazinyl)-, N-oxide (8CI), Cloxazepine N-oxide

Description

Stability Hygroscopic, Light Sensitive
Applications Loxapine N-Oxide is a metabolite of Loxapine (L472750), a D2/D4-Dopamine receptor antagonist. It is a serotonergic receptor antagonist that acts as a dibenzoxazepine antipsychotic agent.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Shen, Y., et al.: J. Biol. Chem., 268, 18200 (1993), Fiorella, D., et al.: Psychopharmacology, 121, 347 (1995), Glusa, E., et al.: Br. J. Pharmacol., 130, 692 (2000)

• Brand: TRC

Chemical properties

• Molecular weight: 343.81
• Formula: C₁₈H₁₈ClN₃O₂
• Color/Form: Neat
• InChI: InChI=1S/C18H18ClN3O2/c1-22(23)10-8-21(9-11-22)18-14-12-13(19)6-7-16(14)24-17-5-3-2-4-15(17)20-18/h2-7,12H,8-11H2,1H3
• InChI key: InChIKey=QUSWANHLDLADDR-UHFFFAOYSA-N
• SMILES: C[N+]1([O-])CCN(C2=Nc3ccccc3Oc3ccc(Cl)cc32)CC1