Loxoprofen Ethoxy Carbonyl Methyl Ester

CAS: 1152440-23-7

Ref. TR-L472945

Product Information

• Name: Loxoprofen Ethoxy Carbonyl Methyl Ester
• Synonyms: ethyl 1-[[4-(1-methoxy-1-oxopropan-2-yl)phenyl]methyl]-2-oxocyclopentane-1-carboxylate

Description

Applications Loxoprofen Ethoxy Carbonyl Methyl Ester is an impurity of Loxoprofen(L472905 ). Loxoprofen is a non-selective nonsteroidal anti-inflammatory drug (NSAID) that has been effective in reducing atherosclerosis in mice by reducing inflammation. Loxoprofen becomes active after metabolism in the body and inhibits the activation of cyclooxygenase.
References Masahide H. et al.: J Clin Biochem Nutr., 47, 138 (2010); Noguchi, M. et al.: Biolog. Pharmac. Bull., 28, 2075 (2005); Hyun, J. et al.: Arch. Pharm. Res., 24, 541 (2001);

• Brand: TRC

Chemical properties

• Molecular weight: 332.391
• Formula: C₁₉H₂₄O₅
• Color/Form: Neat
• InChI: InChI=1S/C19H24O5/c1-4-24-18(22)19(11-5-6-16(19)20)12-14-7-9-15(10-8-14)13(2)17(21)23-3/h7-10,13H,4-6,11-12H2,1-3H3
• InChI key: InChIKey=HJPYJGPAWARAIF-UHFFFAOYSA-N
• SMILES: CCOC(=O)C1(Cc2ccc(C(C)C(=O)OC)cc2)CCCC1=O