Product Information
Name:γ-Lumi (-)-Colchicine
Synonyms:
- Acetamide
- N-[(7S,7bS,10aR)-5,6,7,7b,8,10a-hexahydro-1,2,3,9-tetramethoxy-8-oxobenzo[a]cyclopenta[3,4]cyclobuta[1,2-c]cyclohepten-7-yl]-
- Acetamide
- N-(5,6,7,7b,8,10a-hexahydro-1,2,3,9-tetramethoxy-8-oxobenzo[a]cyclopenta[3,4]cyclobuta[1,2-c]cyclohepten-7-yl)-
- [7S-(7α,7bα,10aα)]-
- γ-Lumicolchicine (6CI,7CI,8CI)
- N-[(7S,7bS,10aR)-5,6,7,7b,8,10a-Hexahydro-1,2,3,9-tetramethoxy-8-oxobenzo[a]cyclopenta[3,4]cyclobuta[1,2-c]cyclohepten-7-yl]acetamide
Brand:TRC
Description:
Applications γ-Lumi (-)-Colchicine is a component of Colchicum species of plants and an electrocyclization product of Colchicine (C640000), an antimitotic agent that disrupts microtubules polymerization.
References Lunduena, R.F., et al.: Curr. Opin. Cell Biol., 4, 53 (1992); Ceccatelli, S., et al.: Neuroreport, 8, 3779 (1997); Want, T.H., et al.: J. Biol. Chem., 273, 4928 (1998); Andreu, J.M., et al.: Biochemistry, 37, 8356 (1998); Jordan, A., et al.: Med. Res. Rev., 18, 259 (1998)
Notice:Our products are intended for lab use only. For any other use, please contact us.
Chemical properties
Molecular weight:399.44
Formula:C22H25NO6
Color/Form:Neat
InChI:InChI=1S/C22H25NO6/c1-10(24)23-13-7-6-11-8-15(27-3)21(28-4)22(29-5)16(11)17-12-9-14(26-2)20(25)18(12)19(13)17/h8-9,12-13,18H,6-7H2,1-5H3,(H,23,24)/t12-,13+,18-/m1/s1
InChI key:InChIKey=VKPVZFOUXUQJMW-LXIYXOSZSA-N
SMILES:COC1=C[C@H]2C3=C([C@@H](NC(C)=O)CCc4cc(OC)c(OC)c(OC)c43)[C@H]2C1=O
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