Lurasidone Opened Imide (Mixture of Diastereomers)

CAS: 1644295-07-7

Ref. TR-L474935

Product Information

• Name: Lurasidone Opened Imide (Mixture of Diastereomers)
• Synonyms: (1S,2R,3S,4R)-3-((((1R,2R)-2-((4-(Benzo[d]isothiazol-3-yl)piperazin-1-yl)methyl)cyclohexyl)methyl)carbamoyl)bicyclo[2.2.1]heptane-2-carboxylic Acid
• Brand: TRC

Description

Applications Lurasidone Opened Imide is an impurity in the synthesis of Lurasidone (L474920) which is antipsychotic used for treatment of schizophrenia.
References Ishiyama, T., et al.: Eur. J. Pharmacol., 572, 160 (2007); Cole, P., et al.: Drugs of the Fut., 33, 316 (2008);

Chemical properties

• Molecular weight: 510.69
• Formula: C₂₈H₃₈N₄O₃S
• Color/Form: Neat
• InChI: InChI=1S/C28H38N4O3S/c33-27(24-18-9-10-19(15-18)25(24)28(34)35)29-16-20-5-1-2-6-21(20)17-31-11-13-32(14-12-31)26-22-7-3-4-8-23(22)36-30-26/h3-4,7-8,18-21,24-25H,1-2,5-6,9-17H2,(H,29,33)(H,34,35)/t18-,19+,20+,21+,24?,25?/m1/s1
• InChI key: InChIKey=QEWPJJKHHCTRAZ-JQQDOLDLSA-N
• SMILES: O=C(O)C1C(C(=O)NC[C@@H]2CCCC[C@H]2CN2CCN(c3nsc4ccccc34)CC2)[C@@H]2CC[C@H]1C2