Product Information
Name:LY2157299
Controlled Product
Synonyms:
- 4-(2-(6-Methylpyridin-2-yl)-5,6-dihydro-4H-pyrrolo[1,2-b]pyrazol-3-yl)quinoline-6-carboxamide
- 4-[5,6-Dihydro-2-(6-methyl-2-pyridinyl)-4H-pyrrolo[1,2-b]pyrazol-3-yl]-6-quinolinecarboxamide
Brand:TRC
Description:Applications LY2157299 is a TGF-β type I receptor kinase inhibitor. LY2157299 has been used to inhance chemotherapy action against triple negative breast cancer (TNBC).References Bhola, N.E., et. al.: J. Clin. Invest., 123, 1348 (2013)
Notice:Our products are intended for lab use only. For any other use, please contact us.
Chemical properties
Molecular weight:369.42
Formula:C22H19N5O
Color/Form:Neat
InChI:InChI=1S/C22H19N5O/c1-13-4-2-5-18(25-13)21-20(19-6-3-11-27(19)26-21)15-9-10-24-17-8-7-14(22(23)28)12-16(15)17/h2,4-5,7-10,12H,3,6,11H2,1H3,(H2,23,28)
InChI key:InChIKey=IVRXNBXKWIJUQB-UHFFFAOYSA-N
SMILES:Cc1cccc(-c2nn3c(c2-c2ccnc4ccc(C(N)=O)cc24)CCC3)n1
Technical inquiry about: LY2157299
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