N-Methyl-6-(4-nitrophenoxy)-4-pyrimidinamine
CAS:
Ref. TR-M106910
10mg
176.00€
50mg
696.00€
100mg
1,129.00€
Product Information
Name:N-Methyl-6-(4-nitrophenoxy)-4-pyrimidinamine
Controlled Product
Brand:TRC
Description:Applications N-Methyl-6-(4-nitrophenoxy)-4-pyrimidinamine is an intermediate in the synthesis of N-[4-[(4-Ethyl-1-piperazinyl)methyl]-3-(trifluoromethyl)phenyl]-N'-[4-[[6-(methylamino)-4-pyrimidinyl]oxy]phenyl]urea (E926495), which is an inhibitor of RET, FLT3, KDR, c-Abl and c-Kit. Also, it prevent the growth of human thyroid cancer cells.References Weisberg, E., et al.: Genes Cancer, 1, 1021-1032 (2010);
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Chemical properties
Molecular weight:246.22
Formula:C11H10N4O3
Color/Form:Neat
InChI:InChI=1S/C11H10N4O3/c1-12-10-6-11(14-7-13-10)18-9-4-2-8(3-5-9)15(16)17/h2-7H,1H3,(H,12,13,14)
SMILES:CNc1cc(Oc2ccc([N+](=O)[O-])cc2)ncn1
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