Product Information
Name:Madecassic Acid
Controlled Product
Synonyms:
- (2α,3β,4α,6β)-2,3,6,23-Tetrahydroxyurs-12-en-28-oic Acid
- Brahmic Acid
- 2α,3β,6β,23-Tetrahydroxy-urs-12-en-28-oic Acid
- 6β-Hydroxyasiatic Acid
- NSC 88135
Brand:TRC
Description:Applications Madecassic Acid is a terpenoid with an ursane skeleton isolated from Centella asiatica. Madecassic Acid displays anti-inflammatory properties as a result of iNOS, COX-2, TNF-alpha, IL-1beta, and IL-6 inhibition via the downregulation of NF-kappaB activation in RAW 264.7 macrophage cells. Madecassic Acid is found in cosmetic products due to its skin-protective activities.References Wonh, J.H. et al.: Planta Med., 76, 251 (2010); Kwon, M.C. et al.: J. Biotechnol., 157, 100 (2012); Loiseau, A. et al.: Cosm. Toil., 115, 63 (2000);
Notice:Our products are intended for lab use only. For any other use, please contact us.
Chemical properties
Molecular weight:504.70
Formula:C30H48O6
Purity:97%
Color/Form:Neat
InChI:InChI=1S/C30H48O6/c1-16-9-10-30(25(35)36)12-11-28(5)18(22(30)17(16)2)7-8-21-26(3)13-20(33)24(34)27(4,15-31)23(26)19(32)14-29(21,28)6/h7,16-17,19-24,31-34H,8-15H2,1-6H3,(H,35,36)/t16-,17+,19-,20-,21-,22+,23-,24+,26-,27+,28-,29-,30+/m1/s1
InChI key:InChIKey=PRAUVHZJPXOEIF-UQPQHHFRSA-N
SMILES:C[C@@H]1C2C3=CCC4[C@@]5(C)C[C@@H](O)[C@H](O)[C@@](C)(CO)C5[C@H](O)C[C@@]4(C)[C@]3(C)CC[C@@]2(C(=O)O)CC[C@H]1C
Technical inquiry about: Madecassic Acid
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