Product Information
Name:MAZ51
Controlled Product
Synonyms:
- 3-[[4-(Dimethylamino)-1-naphthalenyl]methylene]-1,3-dihydro-2H-indol-2-one
- MAZ 51
Brand:TRC
Description:Applications MAZ51 is an indolinone compound that selectively antagonizes the activation of VEGFR-3 by VEGF-C without blocking VEGF-C mediated stumulation of VEGFR-2. This reduces proliferation and induces apoptosis in various cancer cells and suppresses tumor growth.References Kirkin, V. et al.: Eur. J. Biochem., 268, 5530 (2001);
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Chemical properties
Molecular weight:379.408
Formula:C21H18N2O
Color/Form:Neat
InChI:InChI=1S/C21H18N2O/c1-23(2)20-12-11-14(15-7-3-4-9-17(15)20)13-18-16-8-5-6-10-19(16)22-21(18)24/h3-13H,1-2H3,(H,22,24)/b18-13+
Technical inquiry about: MAZ51
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