6-epi-Medroxy Progesterone 17-Acetate

CAS: 2242-65-1

Ref. TR-M203570

Product Information

• Name: 6-epi-Medroxy Progesterone 17-Acetate
• Synonyms: Pregn-4-ene-3,20-dione, 17-(acetyloxy)-6-methyl-, (6ß)-, Pregn-4-ene-3,20-dione, 17-hydroxy-6ß-methyl-, acetate (7CI,8CI), Progesterone, 17-hydroxy-6ß-methyl-, acetate (6CI), (6ß)-17-(Acetyloxy)-6-methylpregn-4-ene-3,20-dione, 6ß-Methyl-17a-hydroxyprogesterone acetate, NSC 119085

Description

Impurity Megestrol EP Impurity F
Applications 6-epi-Medroxy Progesterone 17-Acetate (Megestrol Acetate EP Impurity F) is the epimer of Medroxyprogesterone acetate (M203560). Progesterone (1) impurity. Induces LEFTY expression in normal endometrium cells (2). As a derivative of Progesterone, it may assist in the modulation of ATP-induced calcium signaling in breast cancer cells (3).
References 1. Chang, C. et al.: Steroids. 1968 Dec;12(6):689-96.2. Tang, M. et al.: Endocrinology. 2010 Mar;151(3):1320-303. Lee, K., et al.: Mol. Cell. Endocrinol. 2010 May 5;319(1-2):109-15

• Brand: TRC

Chemical properties

• Molecular weight: 386.52
• Formula: C₂₄H₃₄O₄
• Color/Form: Neat
• InChI: InChI=1S/C24H34O4/c1-14-12-18-19(22(4)9-6-17(27)13-21(14)22)7-10-23(5)20(18)8-11-24(23,15(2)25)28-16(3)26/h13-14,18-20H,6-12H2,1-5H3/t14-,18-,19+,20+,22-,23+,24+/m1/s1
• InChI key: InChIKey=PSGAAPLEWMOORI-PEINSRQWSA-N
• SMILES: CC(=O)O[C@]1(C(C)=O)CC[C@H]2[C@@H]3C[C@H](C)C4=CC(=O)CC[C@]4(C)[C@H]3CC[C@@]21C