TR-M224108 - methyl-4-hydroxy-2-nitrobenzoate | 178758-50-4

<p>Methyl 4-hydroxy-3-nitrobenzoate (HNBP) is a nitro chemical that has been shown to have inhibitory properties. It was found to be a potent inhibitor of the virus covid-19, which is related to the pandemic H1N1 flu. Covid-19 is an influenza A virus that contains a single gene segment encoding for hemagglutinin and neuraminidase. The compound has also shown inhibitory activity against pyridine 2,4 dicarboxylate and is able to form hydrogen bonds with its target. This chemical is not active against many other compounds, such as amides and esters.</p>

<p>Methyl 2-(4-hydroxyisoxazolidin-2-yl)-5-nitrobenzoate</p>

<p>3-Hydroxy-4-methyl-2-nitrobenzoic acid</p>

<p>(E)-2-(1,3-Benzothiazol-2-yl)-3-[4-(dimethylamino)phenyl]prop-2-enenitrile</p>

<p>3-Hydroxy-4-methyl-2-nitrobenzoic acid is an analog of the natural substrate for the enzyme nitroreductase. It can be used in oxidative coupling reactions to generate a covalently bonded product, which is immobilized on sepharose. 3-Hydroxy-4-methyl-2-nitrobenzoic acid has a high affinity for nucleic acids and can be used in biospecific assays. The chromophore of 3-hydroxy-4-methyl-2-nitrobenzoic acid is easily oxidized, leading to its use in nitroreduction reactions in which a nitro group is reduced to an amino group.</p>