Paclitaxel-8-hydro-bicyclo(3.3.0)octane

CAS: 146139-03-9

Ref. TR-M259990

Product Information

• Name: Paclitaxel-8-hydro-bicyclo(3.3.0)octane
• Synonyms: 3H-4,7a-Methanocyclohept[3,3a]indeno[5,4-b]oxete, benzenepropanoic acid deriv., (2R,3S)-3-(Benzoylamino)-2-hydroxy-3-phenylpropanoic acid (1R,2aS,3S,4aR,6aS,6bR,7S,8S,10S,11S,11aR)-1,6a-bis(acetyloxy)-7-(benzoyloxy)dodecahydro-3,8-dihydroxy-2a,11,12,12-tetramethyl-2-oxo-7H-8,11a-methanocyclohept[3,3a]indeno[5,4-b]oxet-10-yl ester, Paclitaxel Photo Degradant, Taxol Photodegradant,Benzenepropanoic acid, β-(benzoylamino)-α-hydroxy-, 2a,8-bis(acetyloxy)-3-(benzoyloxy)dodecahydro-4,10-dihydroxy-7,9a,12,12-tetramethyl-9-oxo-3H-4,7a-methanocyclohept[3,3a]indeno[5,4-b]oxet-6-yl ester, [2aS-[2aα,2bS*,3α,4α,6α(αS*,βR*),7β,7aβ,8β,9aβ,10β,11aα]]- (9CI)
• Brand: TRC
• Description: Applications 3H-4,7a-Methanocyclohept[3,3a]indeno[5,4-b]oxete Benzenepropanoic Acid derivative is an analogue of Paclitaxel (P132500) and has weak antimitotic activity.References Chen, S.H., et. al.: Tetrahedron Lett., 33, 7679 (1992)

Chemical properties

• Molecular weight: 853.91
• Formula: C₄₇H₅₁NO₁₄
• Color/Form: Neat
• InChI: InChI=1S/C47H51NO14/c1-25-31(60-40(56)35(52)34(28-16-10-7-11-17-28)48-38(54)29-18-12-8-13-19-29)23-44(57)41(61-39(55)30-20-14-9-15-21-30)47-43(6,32(51)22-33-45(47,24-58-33)62-27(3)50)36(53)37(59-26(2)49)46(25,47)42(44,4)5/h7-21,25,31-35,37,41,51-52,57H,22-24H2,1-6H3,(H,48,54)/t25-,31+,32+,33-,34+,35-,37+,41-,43+,44-,45+,46-,47-/m1/s1
• InChI key: InChIKey=DVCCAPSSSZMPLX-JAUDPLDNSA-N
• SMILES: CC(=O)O[C@H]1C(=O)[C@]2(C)[C@@H](O)C[C@H]3OC[C@@]3(OC(C)=O)C23[C@H](OC(=O)c2ccccc2)C2(O)C[C@H](OC(=O)[C@H](O)C(NC(=O)c4ccccc4)c4ccccc4)[C@@H](C)C13C2(C)C