Methotrexate a-Methyl Ester (>90%)

CAS: 66147-29-3

Ref. TR-M260700

Product Information

• Name: Methotrexate a-Methyl Ester (>90%)
• Synonyms: L-Glutamic acid, N-[4-[[(2,4-diamino-6-pteridinyl)methyl]methylamino]benzoyl]-, 1-methyl ester, Methotrexate α-methyl ester, Methotrexate 1-Methyl Ester, Methotrexate Imp. I (EP), N-[4-[[(2,4-Diamino-6-pteridinyl)methyl]methylamino]benzoyl]-L-glutamic Acid 1-Methyl Ester, EP Methotrexate Impurity I
• Brand: TRC
• Description: Impurity Methotrexate EP Impurity IApplications Methotrexate α-methyl ester is an impurity of Methotrexate (M260675), a folic acid antagonist. Used as a antineoplastic and antirheumatic. Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the packageReferences Freeman, M.V., J. Pharmacol. Exp. Ther., 122, 154 (1958), Weinblass, M.E., et al.: N. Engl. J. Med., 312, 818 (1985),

Chemical properties

• Molecular weight: 468.47
• Formula: C₂₁H₂₄N₈O₅
• Purity: >90%
• Color/Form: Neat
• InChI: InChI=1S/C21H24N8O5/c1-29(10-12-9-24-18-16(25-12)17(22)27-21(23)28-18)13-5-3-11(4-6-13)19(32)26-14(20(33)34-2)7-8-15(30)31/h3-6,9,14H,7-8,10H2,1-2H3,(H,26,32)(H,30,31)(H4,22,23,24,27,28)/t14-/m0/s1