10α-Methoxy-1-methyl-9,10-dihydrolysergol

CAS: 35155-28-3

Ref. TR-M262295

Product Information

• Name: 10α-Methoxy-1-methyl-9,10-dihydrolysergol
• Synonyms: Nicergoline Imp. C (EP), Methylmethoxylumilysergol, Ergoline-8-methanol, 10-methoxy-1,6-dimethyl-, (8beta)-, Lumilysergol, 10O,1-dimethyl- (7CI), (8beta)-10-Methoxy-1,6-dimethylergoline-8-methanol, Indolo[4,3-fg]quinoline, ergoline-8-methanol deriv., (+)-(5R,10S)-Meluol, 1,6-Dimethyl-8beta-(hydroxymethyl)-10alpha-methoxyergoline, 1-Methyl-10alpha-methoxydihydrolysergol, 10-Methoxy-1,6-dimethylergoline-8beta-methanol, 10alpha-Methoxy-1-methyl-9,10-dihydrolysergol, 10alpha-Methoxy-1-methyldihydrolysergol, O10,1-Dimethyllumilysergol, Nicergoline Impurity C,[(6aR,9R,10aS)-10a-Methoxy-4,7-dimethyl-4,6,6a,7,8,9,10,10a-octahydroindolo[4,3-fg]quinolin-9-yl]methanol (Methylmethoxylumilysergol), [(6aR,9R,10aS)-10a-Methoxy-4,7-dimethyl-4,6,6a,7,8,9,10,10a-octahydroindolo[4,3-fg]quinolin-9-yl]methanol, (8β)-10-Methoxy-1,6-dimethylergoline-8-methanol, 1,6-Dimethyl-10-methoxyergoline-8-beta-methanol, 1,6-Dimethyl-8β-(hydroxymethyl)-10α-methoxyergoline, 1-Methyl-10α-methoxydihydrolysergol, 10α-Methoxy-1-methyldihydrolysergol, Ergoline-8-beta-methanol, 1,6-dimethyl-10-methoxy-, Ergoline-8-methanol, 10-methoxy-1,6-dimethyl-, (8β)-, Indolo[4,3-fg]quinoline, ergoline-8-methanol deriv., Lumilysergol, ¹⁰O,1-dimethyl-, O¹⁰,1-Dimethyllumilysergol, [(8Beta,10Xi)-10-Methoxy-1,6-Dimethylergolin-8-Yl]Methanol, Lumilysergol, 10O,1-dimethyl-

Description

Impurity Nicergoline EP Impurity C
Applications 10α-Methoxy-1-methyl-9,10-dihydrolysergol is a nicergoline (N394550) metabolite that has been shown to have antioxidant activity, preventing glutathione (GSH) depletion and lipid peroxidation; thus it has shown potential as treatment of neuroleptic-induced side effects.
References Vairetti, M., et. al.: Eur. J. Pharmacol., 453, 69 (2002)

• Brand: TRC

Chemical properties

• Molecular weight: 300.40
• Formula: C₁₈H₂₄N₂O₂
• Color/Form: Neat
• InChI: InChI=1S/C18H24N2O2/c1-19-10-13-7-16-18(22-3,8-12(11-21)9-20(16)2)14-5-4-6-15(19)17(13)14/h4-6,10,12,16,21H,7-9,11H2,1-3H3/t12-,16-,18+/m1/s1
• InChI key: InChIKey=LVXVIPZBNJSUKL-NJAPINKUSA-N
• SMILES: CO[C@]12C[C@@H](CO)CN(C)[C@@H]1Cc1cn(C)c3cccc2c13